Acid Base Homeostasis Lab Report
INTRODUCTION
Maintaining blood pH is so important to keep our body healthy. The internal pH for most of living thing is close to 7. The normal pH of human blood is between 7.35 and 7.45. A person cannot survive for more than a few minutes if the blood pH drops or rise from the normal blood pH. If the blood pH is not in the normal blood pH, the person can fall sick and it might be harm to the person. The maintenance of blood pH is called acid-base homeostasis. Acid-base homeostasis is a complex synergy that involving lungs, kidneys and a buffer chemical in blood and blood cells.
BACKGROUND A substance that has high concentration of hydrogen ion in solution is called acid and solution that has low concentration of hydrogen ion is base. Base …show more content…
Processing of filtrate in proximal tubule helps in maintaining a relatively constant pH in blood. Cells of the transport epithelium secrete hydrogen ion into the lumen of the tubule but also synthesize and secrete ammonia. Ammonia is a buffer that trap hydrogen ion in the form of ammonium ions. The more ammonia secrete, the more acidic the filtrate and the blood will be less acidic. That is why mostly urine contains ammonia. The proximal tubule also reabsorb the buffer of bicarbonate from filtrate due to pH balance in blood. The filtrate will continue to descending limb of the loop of Henle and then to ascending limb of the loop of Henle. After that, the blood will filtrate at distal tubule. The distal tubule also contributes in pH regulation by control the secretion of hydrogen ions and reabsorption of bicarbonate ions. The last process in nephron is collecting duct. This process is filtrate into urine. All the substances that have been filtrate will secrete into …show more content…
Lungs control blood pH faster than kidneys. It takes minute to minute to regulate the blood ph. Breathing can be voluntarily or involuntarily. Mostly our lungs will function involuntarily. The neurons in the medulla oblongata, that near the base of brain is responsible for regulating breathing. The medulla uses the pH of the fluid to regulating breathing. When the blood pH falls due to rising levels of carbon dioxide (CO2) in tissues, sensors in major blood vessels will detect decrease in blood pH and send it to medulla. The medulla will send signals to rib muscles and diaphragm to increase the rate and depth of breathing. Booth remain high until the excess carbon dioxide is eliminated in exhaled air and the pH became normal state. Carbon dioxide can increase the pH when the carbon dioxide is diffuses from blood to the cerebrospinal fluid. Cerebrospinal fluid is a fluid found in brain and spinal cord. Carbon dioxide will reacts with water and forms carbonic acid (H2CO3). The carbonic acid can dissociate into a bicarbonate ion (HCO3-) and hydrogen ion
Maintaining blood pH is so important to keep our body healthy. The internal pH for most of living thing is close to 7. The normal pH of human blood is between 7.35 and 7.45. A person cannot survive for more than a few minutes if the blood pH drops or rise from the normal blood pH. If the blood pH is not in the normal blood pH, the person can fall sick and it might be harm to the person. The maintenance of blood pH is called acid-base homeostasis. Acid-base homeostasis is a complex synergy that involving lungs, kidneys and a buffer chemical in blood and blood cells.
BACKGROUND A substance that has high concentration of hydrogen ion in solution is called acid and solution that has low concentration of hydrogen ion is base. Base …show more content…
Processing of filtrate in proximal tubule helps in maintaining a relatively constant pH in blood. Cells of the transport epithelium secrete hydrogen ion into the lumen of the tubule but also synthesize and secrete ammonia. Ammonia is a buffer that trap hydrogen ion in the form of ammonium ions. The more ammonia secrete, the more acidic the filtrate and the blood will be less acidic. That is why mostly urine contains ammonia. The proximal tubule also reabsorb the buffer of bicarbonate from filtrate due to pH balance in blood. The filtrate will continue to descending limb of the loop of Henle and then to ascending limb of the loop of Henle. After that, the blood will filtrate at distal tubule. The distal tubule also contributes in pH regulation by control the secretion of hydrogen ions and reabsorption of bicarbonate ions. The last process in nephron is collecting duct. This process is filtrate into urine. All the substances that have been filtrate will secrete into …show more content…
Lungs control blood pH faster than kidneys. It takes minute to minute to regulate the blood ph. Breathing can be voluntarily or involuntarily. Mostly our lungs will function involuntarily. The neurons in the medulla oblongata, that near the base of brain is responsible for regulating breathing. The medulla uses the pH of the fluid to regulating breathing. When the blood pH falls due to rising levels of carbon dioxide (CO2) in tissues, sensors in major blood vessels will detect decrease in blood pH and send it to medulla. The medulla will send signals to rib muscles and diaphragm to increase the rate and depth of breathing. Booth remain high until the excess carbon dioxide is eliminated in exhaled air and the pH became normal state. Carbon dioxide can increase the pH when the carbon dioxide is diffuses from blood to the cerebrospinal fluid. Cerebrospinal fluid is a fluid found in brain and spinal cord. Carbon dioxide will reacts with water and forms carbonic acid (H2CO3). The carbonic acid can dissociate into a bicarbonate ion (HCO3-) and hydrogen ion