A Review of the Literature
Fariha Shafaat
Jinnah University for Women
Author Note
This paper was prepared for Research Methodology, course no. 4191, taught by Professor Dr.Rana Hadi.
ABSTRACT
In this report an attempt has been made to analyze the Systematic search of the medical literature to identify studies that used antibiotics in randomized controlled trials to treat acute otitis media. Studies were examined blind, and the results of those of satisfactory quality of methodology were pooled. Pain, deafness, and other symptoms related to acute otitis media or antibiotic treatment. Antibiotics reduced contralateral acute otitis media by 43% (9% to 64%). They seemed to have no influence on subsequent attacks of otitis media or deafness at one month, although there was a trend for improvement of deafness at three months. Antibiotics were associated with a near doubling of the risk of vomiting, diarrhoea, or rashes.
Antibiotic Treatment for Acute Otitis Media in Children
A Review of the Literature
Otitis media or "inflammation of the middle ear" is the medical term for middle ear infection. Although several subtypes of otitis media are distinguished, the term is often used synonymously with acute otitis media. It is very common in childhood.
The common cause of all forms of otitis media is blockage of the Eustachian tube. This is usually due to swelling of the mucous membranes in the nasopharynx, which in turn can be caused by a viral upper respiratory infection or by allergies. Because of the blockage of the Eustachian tube, the air volume in the middle ear is trapped and parts of it are slowly absorbed by the surrounding tissues, leading to a mild vacuum in the middle ear. Eventually the vacuum can reach a point where fluid from the surrounding tissues is sucked in to the middle ear 's cavity (also called tympanic cavity), causing middle ear effusion. This is seen as a progression from a
References: 1. Bain J. Controversies in therapeutics: Childhood otalgia: justification for antibiotic use in general practice. BMJ. 1990;300:1006–1007. 2. Browning G 3. Froom J, Culpepper L, Jacobs M. Antimicrobials for acute otitis media? A review from the international primary care network. BMJ. 1997;315:98–102. 4. Del Mar C, Glaziou P, Hayem M 5. Burke P, Bain J, Robinson D, Dunleavey J. Acute red ear in children: controlled trial of non-antibiotic treatment in general practice. BMJ. 1991;303:558–562. 6. Little PS, Williamson I, Warner G, Gould C, Gantley M, Kinmonth AL 13. Gates G, Northern J, Ferrer P. Diagnosis and screening. Ann Otolo Laryngol. 1989;98(suppl 139):39–41. 16. Ruuskanen O, Heikkinen T. Otitis media: etiology and diagnosis. Pediatr Infect Dis J. 1994;13:s23–6. 23. Kudo F, Sasamura Y. Acute mastoiditis in infants: penicillin-resistant Streptococcus pneumoniae and its therapy. Nippon Jibiinkoka Gakkai Kaiho. 1998;101:1075–1081. 24. Collison P, Farver D 25. Antonelli P, Dhanani N, Giannoni C, Kubilis P. Impact of resistant pneumococcus on the rates of acute mastoiditis. Otolaryngol Head Neck Surg. 1999;121:190–194. 26. Cates C