Adolescent Idiopathic Scoliosis Research Paper

It took me a while to discover a health problem/condition that I have as well as it being persistent through three generations of my family. My father and both of his parents have high blood pressure, but mine sits low and a take medication to keep it raised. My mother and my grandmother both have the BCA2 or otherwise known as the Breast Cancer-Associated Gene 2. This encodes a RING-finger ubiquitin E3 ligase, which is associated with the estrogen receptor (ER)- a positive status in human breast tumors, so basically it tells them they have an increased chance in developing breast cancer, but I have never been tested for the gene. (Kona, F. R., Stark, K., Bisoski, L., Buac, D., Cui, Q., & Dou, Q. P.) Finally, I came across the fact that I have scoliosis, even though it is mild, as well as my mother and my grandmother. Scoliosis or otherwise known as adolescent idiopathic scoliosis is an abnormal curvature of the spine that appears in late childhood or adolescence. Instead of growing straight, the spine develops a side-to-side curvature and the bones of the spine are also slightly twisted or rotated. (“Adolescent idiopathic scoliosis -
At least four percent of scoliosis curves progress to the point of the patient needing surgery, yet only one percent of patients have a high genetic risk of severe curvature. If genes are a factor in only one percent of cases, environmental factors must account for the severity in the other three percent. However, scientists have not discovered what those environmental factors may be for slouching, carrying heavy bookbags, and living in industrial areas have all been ruled out when seeing if it held any relation to spinal curvature. (“Is Scoliosis Hereditary, Genetic or Environmental?” 2017, January