Preview

Advanced Drug Formulation and Design

Powerful Essays
Open Document
Open Document
40827 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Advanced Drug Formulation and Design
Advanced Drug Formulation Design to Optimize Therapeutic Outcomes

DRUGS AND THE PHARMACEUTICAL SCIENCES
A Series of Textbooks and Monographs

Executive Editor James Swarbrick
PharmaceuTech, Inc. Pinehurst, North Carolina

Advisory Board
Larry L. Augsburger
University of Maryland Baltimore, Maryland

Harry G. Brittain
Center for Pharmaceutical Physics Milford, New Jersey

Jennifer B. Dressman
Johann Wolfgang Goethe University Frankfurt, Germany

Anthony J. Hickey
University of North Carolina School of Pharmacy Chapel Hill, North Carolina

Jeffrey A. Hughes
University of Florida College of Pharmacy Gainesville, Florida

Ajaz Hussain
Sandoz Princeton, New Jersey

Trevor M. Jones
The Association of the British Pharmaceutical Industry London, United Kingdom

Stephen G. Schulman
University of Florida Gainesville, Florida

Elizabeth M. Topp
University of Kansas School of Pharmacy Lawrence, Kansas

Vincent H. L. Lee
University of Southern California Los Angeles, California

Jerome P. Skelly
Alexandria, Virginia

Peter York
University of Bradford School of Pharmacy Bradford, United Kingdom

Geoffrey T. Tucker
University of Sheffield Royal Hallamshire Hospital Sheffield, United Kingdom

1. Pharmacokinetics, Milo Gibaldi and Donald Perrier 2. Good Manufacturing Practices for Pharmaceuticals: A Plan for Total Quality Control, Sidney H. Willig, Murray M. Tuckerman, and William S. Hitchings IV 3. Microencapsulation, edited by J. R. Nixon 4. Drug Metabolism: Chemical and Biochemical Aspects, Bernard Testa and Peter Jenner 5. New Drugs: Discovery and Development, edited by Alan A. Rubin 6. Sustained and Controlled Release Drug Delivery Systems, edited by Joseph R. Robinson 7. Modern Pharmaceutics, edited by Gilbert S. Banker and Christopher T. Rhodes 8. Prescription Drugs in Short Supply: Case Histories, Michael A. Schwartz 9. Activated Charcoal: Antidotal and Other Medical Uses, David O. Cooney 10. Concepts in Drug Metabolism
Continue Reading
View Writing Issues

You May Also Find These Documents Helpful

  • Good Essays

    Separting the Components of Panacetin
    • 305 Words
    • 2 Pages

    Separting the Components of Panacetin

    The purpose of this experiment is to investigate the composition of a simulated pharmaceutical preparation Panacetin, a proposed type of pain-killer. Panacetin is typically made up of sucrose, aspirin, and acetaminophen, but the third component in this experiment is unknown. The unknown component is suspected to be a chemical relative of acetaminophen, either acetanilide or phenacetin. Using techniques such as extraction, evaporation, and filtration, the three components will be isolated based on their solubilities and acid-base properties. The percent composition of Panacetin will also be deduced based on the masses of the three dried components; this is done to verify the composition attained is consistent with those listed on the preparations label. As a result of this investigation, my teammates and I allowed the Panacetin to undergo gravity filtration and separation techniques in order to identify whether there are any discrepancies in the components of the Panacetin. Furthermore, recrystallization and purification methods were used to determine if the unknown substance were similar in properties to either of the suspected unknown substances by comparing factors such as melting points to the chemical properties of phenactin and acetanilide. The results were as expected, based on the molecular weights and ratios of each separated chemicals, as well as the boiling point of the unknown it was determined that these ranges were close enough to indicate that the label is reasonably accurate in its composition. To add on however the identity of the unknown component differed from what the label indicated. In the end, the percentage composition attained based on our observations and yield confirmed that indeed the chemical composition of Panacetin were as indicated on the preparations label. The identity of the unknown component however suggested that the preparation did not contain acetaminophen as indicated, but instead was consistent with the chemical properties…

    • 305 Words
    • 2 Pages
    Good Essays
    Read More
  • Better Essays

    Eco 561 Wk 4
    • 1761 Words
    • 8 Pages

    Eco 561 Wk 4

    Recently many drug companies are attempting to create a better lifestyle treatment plan for their target patients. They are focusing on developing their IV chemotherapies into pills. This lets the…

    • 1761 Words
    • 8 Pages
    Better Essays
    Read More
  • Satisfactory Essays

    Hcs/ 490 Outline
    • 475 Words
    • 2 Pages

    Hcs/ 490 Outline

    References: Division of Drug Marketing, Advertising, and Communications (DDMAC). 2010. Retrieved August 6, 2010 from http://www.fda.gov/AboutFDA/CentersOffices/CDER/ucm090142.htm Food and Drug Administration (2010). Division of Drug, Marketing, Advertising, and Communications. Retrieved from http://www.fda.gov/AboutFDA/CentersOffices/CDER/ucm090142.htm Us Food and Drug Administration. (2010). Retrieved August 9, 2010 from website: http://www.fda.gov/AboutFDA/WhatWeDo/default.htm US Food and Drug Administration (2010). “Inspection, Compliance, Enforcement and Criminal Investigations.” Retrieved August 16, 2010 from www.hhs.gov.…

    • 475 Words
    • 2 Pages
    Satisfactory Essays
    Read More
  • Powerful Essays

    Research Paper SUB606
    • 2721 Words
    • 9 Pages

    Research Paper SUB606

    Drugs affect many areas of a person’s body, the central nervous system (CNS) is effected “causing mental, emotional and physical changes” (Inaba & Cohen, 2011). Pharmacokinetics describes this process by which a drug is “absorbed, distributed, metabolized, eliminated, and excreted by the body” (Inaba & Cohen, 2011). The…

    • 2721 Words
    • 9 Pages
    Powerful Essays
    Read More
  • Good Essays

    National Woman's Party
    • 265 Words
    • 2 Pages

    National Woman's Party

    The National Woman’s Party was formed in 1916 by american women. This movement was branched off from the Congressional Union, The National Woman's Party, like the Congressional Union, was controlled by Alice Paul, a activist in rights for women, used publicity to target the Democrat party to gain publicity. This created many conflict between authority and protestors but was fought for a good cause for women's rights.…

    • 265 Words
    • 2 Pages
    Good Essays
    Read More
  • Powerful Essays

    How Did Penicillin Help the Allies Win Wwii?
    • 2117 Words
    • 9 Pages

    How Did Penicillin Help the Allies Win Wwii?

    "The Drug Safety." The Drug Safety. The Drug Society, 2011. Web. 26 Sept. 2011. .…

    • 2117 Words
    • 9 Pages
    Powerful Essays
    Read More
  • Powerful Essays

    help in language distribution
    • 4301 Words
    • 18 Pages

    help in language distribution

    The active ingredients in drugs and medicines can be isolated from a plants and animals or synthesized artificially.…

    • 4301 Words
    • 18 Pages
    Powerful Essays
    Read More
  • Powerful Essays

    Professional Ethics Pharmacist s Right to Refuse to Dispense
    • 2878 Words
    • 7 Pages

    Professional Ethics Pharmacist s Right to Refuse to Dispense

    Pharmacy is a noble respected profession guided by strict laws and regulations. Pharmacists are the care providers who are responsible to provide drug therapies that improve the quality of life of a patient and their family. Previously pharmacists were only thought to be a drug dispenser but now they are the care providers of the community (Lai, Trac, Lovett, 2013). In the 1800s, pharmacists played the role of apothecary, a medical professional that prepared and sold drugs in earlier times (Lai, Trac, Lovett, 2013). Towards the end of the 1900s to the present, pharmacists have focused on responding to manage care and new concerns about the quality of patient care (Lai, Trac, Lovett, 2013).…

    • 2878 Words
    • 7 Pages
    Powerful Essays
    Read More
  • Powerful Essays

    Case Study Formulation Drug and Alcohol
    • 1254 Words
    • 6 Pages

    Case Study Formulation Drug and Alcohol

    Although it was previously thought that cannabis was not a drug of addiction, it is now recognized that cannabis use can lead to substance dependence, according to the internationally accepted DSM-IV definition of ‘substance dependence’ .…

    • 1254 Words
    • 6 Pages
    Powerful Essays
    Read More
  • Better Essays

    Fda Research Paper
    • 2368 Words
    • 10 Pages

    Fda Research Paper

    Americans must wait up to 19 years after a discovered treatment before they can participate in benefits of a new medication (Philipson & Sun, 2008). The regulatory process drug manufacturers need to endure before releasing potentially life-saving medication is an extremely expensive, time-consuming process. The Center for Drug Evaluation and Research (CDER) is the main department of the Food and Drug Administration (FDA) responsible for the safety of drugs (both prescription and over-the-counter) sold in the United States (Food and Drug Administration, 2011). This department scrutinizes the testing of new drugs and determines if they are safe and effective before distribution. They do not perform in-house testing themselves; they only evaluate the testing done by the manufacturer to make sure the drug claim is accurate and that the benefits of the medication out way the side-effects (Food and Drug Administration, 2011). Whereas the FDA’s regulation and oversight protects dangerous products from circulation, the approval process hinders manufacturers’ ability to release drugs in a timely manner because of the legal and cost liability, thus preventing the availability of treatment to Americans.…

    • 2368 Words
    • 10 Pages
    Better Essays
    Read More
  • Powerful Essays

    Omeprazole
    • 1704 Words
    • 6 Pages

    Omeprazole

    Omeprazole was one of the first proton pump inhibitors bought onto the market in the late 1980’s, they appear to be the drug of choice for most gastric related disorders (Der, 2003)…

    • 1704 Words
    • 6 Pages
    Powerful Essays
    Read More
  • Good Essays

    Cholesterol
    • 682 Words
    • 3 Pages

    Cholesterol

    Joint Formulary Committee. (2011). British National Formulary. (61st ed). London: British Medical Association & Royal Pharmaceutical Society of Great Britain.…

    • 682 Words
    • 3 Pages
    Good Essays
    Read More
  • Good Essays

    Alzheimers disease
    • 735 Words
    • 8 Pages

    Alzheimers disease

    (2013). Pharmacotherapeutics for advanced practice: A practical approach (3rd ed.). Amber, PA: Lippincott Williams & Wilkins.…

    • 735 Words
    • 8 Pages
    Good Essays
    Read More
  • Better Essays

    Pathway to Success
    • 1216 Words
    • 5 Pages

    Pathway to Success

    "Texas Tech University Health Science Center School of Pharmacy". ©2010 Texas Tech University Health Sciences Center . May 5, 2010 <http://www.ttuhsc.edu/sop/contacts.aspx>.…

    • 1216 Words
    • 5 Pages
    Better Essays
    Read More
  • Good Essays

    Essay On Medication Errors
    • 517 Words
    • 3 Pages

    Essay On Medication Errors

    Medication play an important role in the health of millions, yet many challenges prevent their great use. Drug Safety specializes in reviews on the epidemiology, clinical features, prevention and management of adverse effects of individual drugs and drug classes. Some adverse effects of medicines only come to light after medications have been on the market and widely used. Investigators are working to develop new methods for identifying risk, to…

    • 517 Words
    • 3 Pages
    Good Essays
    Read More

Related Topics