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Alzheimer's Disease. U.S. National Library of Medicine

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Alzheimer's Disease. U.S. National Library of Medicine
Alzheimer’s Disease | January 16
2013
| Alzheimer 's disease is a progressive neurologic disease of the brain leading to the irreversible loss of neurons and the loss of intellectual abilities, including memory and reasoning, which become severe enough to impede social or occupational functioning.

The brain is the center of the nervous system. It controls all of our nerves. The brain is also able to hold memory and language. Dementia is a loss of brain function that occurs with certain diseases. It affects memory, thinking, language, judgment, and behavior. The most common type of Dementia is Alzheimer’s disease. Fifty to Eighty percent of people with Dementia have the case of Alzheimer’s disease. What is Alzheimer’s disease? It is the loss of neurons that you can’t get back. Alzheimer’s disease eventually gets worse over time.
What causes Alzheimer’s disease? Scientists believe that people get Alzheimer’s disease from lifestyle and environmental factors that affect the brain over time. In 1991, the amyloid hypothesis assumed that beta-amyloid deposits are the fundamental cause of the disease. They eventually found a vaccine to take away amyloid plaques and used it on humans. It didn’t seem to affect the cause of dementia. The oldest hypothesis, the cholinergic hypothesis, hypothesizes that Alzheimer’s disease is caused by reduced synthesis of acetylcholine. People based their medicines or drugs on this hypothesis. Although, many people do not find this hypothesis effective because many people discovered that the drugs weren’t as effective. Genetics can also cause Alzheimer’s disease. It isn’t because it is inherited, but it can become a risk factor. It is known as early onset familial Alzheimer’s disease. ” The best known genetic risk factor is the inheritance of the ε4 allele of the apolipoprotein E (APOE). “ – Wikipedia. Between 40 to 80 percent of people with Alzheimer’s disease has at least one APOEε4 allele. The way doctors can tell if you have



Cited: "Alzheimer 's Disease & Dementia | Alzheimer 's Association." Alzheimer 's Disease & Dementia | Alzheimer 's Association. N.p., n.d. Web. 16 Jan. 2013. "Alzheimer 's Disease." Wikipedia. Wikimedia Foundation, 15 Jan. 2013. Web. 17 Jan. 2013. Board, A.D.A.M. Editorial. "Alzheimer 's Disease." Alzheimer 's Disease. U.S. National Library of Medicine, 18 Nov. 0000. Web. 16 Jan. 2013. Nordqvist, Christian. "What Is Alzheimer 's Disease? What Causes Alzheimer 's Disease?" Medical News Today. MediLexicon International, 31 July 2009. Web. 16 Jan. 2013.

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