AmgenCaseStudy
Case Study: !
From humble beginnings to world’s largest biotech
September
29, 2104
•
1980
Today:
•
•
1982
1983
!
Amgen
is world’s largest biotechnology company
•
1984
•
1985
Deal exclusively with biologics
•
1987
•
1989
•
1991
20,000 global employees in North America, Europe, Asia, Australia, and Middle East
Over
$18 billion in annual sales
43%
of revenue still from first 2 drugs:
Neupogen
Epogen
• 2014
Biologics: medicinal products manufactured or extracted from biological sources-used extensively for producing regenerative medicines
•
1980
•
•
1982
1983
•
1984
•
1985
•
1987
•
1989
•
1991
• 2014
This is the story of
the development of Epogen !
World’s
first biotech blockbuster drug !
Made
Amgen who they are today
•
1980
•
•
1982
1983
•
1984
•
1985
•
1987
•
1989
•
1991
What is Epogen?
Mimics
naturally occurring hormone erythropoietin (EPO)
EPO-‐
gene that prevents anemia
EPO-‐
Produced in the kidneys
Stimulates
RBC production
Carries
oxygen around the body
•
2014
EPO is a gene that prevents anemia. Anemia can affect people with Chronic Kidney Disease, but also therapy for patients receiving chemotherapy treatment. Anemia leads to severe fatigue and increased risk of cardiovascular disease and even death.
• 1980
•
•
1982
1983
•
1984
•
1985
•
1987
•
1989
•
1991
•
2014
In the beginning
1980:
Co-‐Founded by William Bowes & Franklin Johnson.
Name: Applied Molecular Genetics (AMGEN)
Bowes
raises $200,000 in seed capital
Bowes
makes keystone decision:
Hires
George Rathmann, as CEO
1980: William Bowes left the world’s first biotech
From humble beginnings to world’s largest biotech
September
29, 2104
•
1980
Today:
•
•
1982
1983
!
Amgen
is world’s largest biotechnology company
•
1984
•
1985
Deal exclusively with biologics
•
1987
•
1989
•
1991
20,000 global employees in North America, Europe, Asia, Australia, and Middle East
Over
$18 billion in annual sales
43%
of revenue still from first 2 drugs:
Neupogen
Epogen
• 2014
Biologics: medicinal products manufactured or extracted from biological sources-used extensively for producing regenerative medicines
•
1980
•
•
1982
1983
•
1984
•
1985
•
1987
•
1989
•
1991
• 2014
This is the story of
the development of Epogen !
World’s
first biotech blockbuster drug !
Made
Amgen who they are today
•
1980
•
•
1982
1983
•
1984
•
1985
•
1987
•
1989
•
1991
What is Epogen?
Mimics
naturally occurring hormone erythropoietin (EPO)
EPO-‐
gene that prevents anemia
EPO-‐
Produced in the kidneys
Stimulates
RBC production
Carries
oxygen around the body
•
2014
EPO is a gene that prevents anemia. Anemia can affect people with Chronic Kidney Disease, but also therapy for patients receiving chemotherapy treatment. Anemia leads to severe fatigue and increased risk of cardiovascular disease and even death.
• 1980
•
•
1982
1983
•
1984
•
1985
•
1987
•
1989
•
1991
•
2014
In the beginning
1980:
Co-‐Founded by William Bowes & Franklin Johnson.
Name: Applied Molecular Genetics (AMGEN)
Bowes
raises $200,000 in seed capital
Bowes
makes keystone decision:
Hires
George Rathmann, as CEO
1980: William Bowes left the world’s first biotech