November 22, 2014
AP Biology: 4th Hour
Mitosis & Meiosis Test Corrections
3.) At which phase are centrioles beginning to move apart in animal cells? E. Prophase
This answer can be found in the book on page 232, “Prophase – centrosomes move away from each other, propelled partly by the lengthening microtubules between them.”
4.) If cells in the process of dividing are subjected to colchicine, a drug that interferes with the formation of the mitotic spindle apparatus, at which stage will mitosis be arrested? D. Metaphase This answer can be found on page 233, Figure 12.7.
5.) Where do the microtubules of the spindle originate during mitosis in animal cells? B. Centrosome
This answer can be found on page 232, “Prophase - The mitotic spindle begins to form. IT is composed of the centrosomes and microtubules that extend from them.”
6.) Taxol is an anticancer drug extracted from the pacific yew tree. In animal cells, Taxol disrupts microtubule formation by binding to microtubules and accelerating their assembly from the protein precursor, tubulin. Surprisingly, this stops mitosis. Specifically, Taxol must affect… A. Formation of the mitotic spindle
This answer is A, because the drug Taxol disrupts microtubule formation, without microtubule formation the mitotic spindle will not be able to form.
8.) Why do chromosomes coil during mitosis? B. To allow the chromosomes to move without becoming entangled and breaking This answer can be found in the book on page 229, Figure 12.3.
12.) Which of the following is true concerning cancer cells?
E. When they stop dividing, they do so at random points in the cell cycle; they are not subject to cell cycle controls; and they do not exhibit density-dependent inhibition when growing in culture. This answer can be found in the book on page 241, Figure 12.19.
15.) What is the correct chromosomal condition at the prometaphase of mitosis? B. B This answer can be found on page 232, Figure 12.7.
16.) What is the