Bone Remodeling Research Paper

Bone remodeling is the process by which osteoclasts eat old bone and stimulate osteoblasts to make new bone. Most bones begin as cartilage and fibrous structures. Calcified bone matrix replaces the cartilage and real bone formation begins to occur. The bone-resorbing cells called osteoclasts and bone-forming cells called osteoblasts work constantly to sculpture and remodel growing bones as they transition from cartilage to adult bones. Osteocytes are mature, nondividing osteoblasts that have become surrounded by matrix and now lie within lacunae. Bone formation begins with cartilage in the long bones. Ossification of long bones occurs as bone tissue replaces cartilage. With the combined action of osteoblasts (the bone forming cells) and osteoclasts