10.9% of all cancer patients, including men and women, belong to the breast cancer community. Breast cancer occurs frequently in women, though, 1% of all breast cancer patients are men (Boyle & Levin, 2008). According to IARC records, a total of 1,677,000 incidents of breast cancer have been reported in both developing and developed countries in 2012 (International Agency for Research on Cancer, 2013). While breast cancer ranks fifth among the causes of mortality due to cancer (522,000 deaths in 2012), it is still the most significant cause of cancer death among women (International Agency for Research on Cancer, 2013).
Breast cancer has been reported as the second-most …show more content…
According to the American
Cancer Society Statistical reports, approximately one in eight women in the US contract breast cancer throughout their life (American Cancer Society, 2012). Despite the many statistical records showing the fast-growing prevalence of breast cancer during the last decade, evidence suggests that the risk of death from breast cancer has been reduced among women aged 40 to 49 who undergo annual mammography (Boyle & Levin,
2008). Although mammography is an effective method of early detection of breast cancer after menopause, it is not very effective for young women, who have dense breasts and are at risk of inherited syndrome. Additionally, mammography has low specificity (80% of false positive cases) in distinguishing malignant from benign tumors
(Mehrabian, 2008). Therefore, diverse pathological research regimes have been established to enhance methods of early detection of cancer in women, both young and old. 2
1.1. Anatomy of the Breast
The human female breast consists mainly of mammary glands, adipose (fat) and connective tissues. As presented in Figure 1, the mammary glands contain a series of milk ducts and some interconnected lobules, forming 15 to 20 lactiferous ducts that