Adjustable insulin regime Sulfonylureas - FXN - Improve insulin secretion from pancreatic beta cells. Biguanides - FXN - reduces hepatic glucose output Thiazolidinediones (TZD) - FNX - increase insulin sensitivity DPP-4 Inhibitors - FXN- slows the inactivation of incretin hormones, increasing insulin release Exenatide (Byetta) 2x - FNX - synthetic protein in saliva to stimulate insulin production Liraglutide (Victoza) 1x - FXN -stimulate insulin production Rapid acting insulin - onset 5-15min/peak 1-2hr/ duration 6-10hr Short acting insulin- onset 30-60min/peak 2-4hr/ duration 6-10hr Intermediate Insulin - onset 1-2hr/peak 4-8hr/ duration 10-18h // Long Acting Insulin onset 1-2hr/ Risk Factors and Prognosis in Hypertension hypercholesterolemia, obesity, ETOH intake, end-organ…
Who is the greatest Canadian in History? Tommy Clement Douglas, the Father of Medicare without doubts. One can be qualify and granted with the title ‘Greatest Canadian in History’ when Canadians be proud of the legacy one has created. An online survey conducted by Leger Marketing has shown that 94 percent of Canadians thinks that Canada’s Universal Health Care created by Tommy Douglas is the most important pride as a Canadian; even though Europe too has Universal Health Care for their citizens. Although many may vote for national hero Terry Fox for his contribution to cancer research or Nobel prize winner Sir Frederick Banting for the invention of Insulin as the Greatest Canadian in History. However, it was Tommy Douglas who made Universal…
That is exactly what Bondar did through her work, both medical and astronautical; Bondar had made significant contributions through her research that has lead to advancements in technology. One significant example of Bondar’s contribution was during her time at NASA when she led an international space medicine research team. During this mission, Bondar and her colleagues found connections between astronauts recovering from the microgravity of space and neurological illness on Earth such as Parkinson's and stroke. These discoveries have been used in clinical studies in prestigious schools such as the Deaconess Medical School and University of New Mexicol. This shows how Bondar’s research was valued at an international level by many reputable medical centres. Subsequently, this shaped Canada’s identity as Bondar was one of the leading scientists of this experiment. Another great example of Bondar’s legacy is through her written books, Touching the Earth, and On The Shuttle: Eight Days In Space and also through her visual books, The Arid Edge of Earth, Canada: Landscape of Dreams, and Passionate Vision: Discovering Canada's National Parks. This proves that Bondar has a strong legacy as many of the photographs from her visual books were presented in art galleries and many of her books are widely popular around the world. This also shows how Bondar is willing to apply her insights to help others adapt to the uncharted territory, and many of her books also prove how lessons from space can be applied to today’s constantly changing world. Through these substantial contributions, Bondar had created a solid legacy that will be remembered for years to come. It is also due to these contributions that Bondar is known to have a positive influence on Canada’s…
In January of 1922, Dr. John Macleod walked into a small high-ceilinged room surrounded by crisp white walls and a small blue cot. On that cot lay a gaunt-faced young boy named Leonard Thompson. He was barely 14 years old , in a coma, and slowly dying from a previously incurable disease. Macleod had been testing a hormone that could cure this boy and people just like him from their life threatening illness, but had been unsuccessful in finding something that would help. However, today was a very big day. Macleod had finally gotten a pure enough sample of dog insulin that he could give it to this boy.…
At the time, diabetes was a disorder that can kill you as there was no cure for it. His interest grew when he found out that diabetes was a blood disorder, when he read in an article that diabetes happened when the sugar level in the bloodstream rose a great amount (“Frederick Banting Biography”). Banting then had an idea, an idea that changed the world. He knew from lectures that there was a substance in the pancreas that can control the sugar in the bloodstream, now known to us as insulin so he thought if he could give this substance to patients, he will be able to treat diabetes (“Sir Frederick…
Sir Frederick Grant Banting was one of the greatest Canadians in history. He was born on November 14, 1891 near Alliston Ontario, and died in 1941 at the age of 50. After serving as a medical officer in France during the First World War, Frederick Banting was awarded the Military Cross for his bravery. He was also responsible for one of the greatest achievements in medical history, the discovery of insulin in 1922. He had saved the lives of countless diabetics throughout the world. Frederick Banting won the first Nobel Prize for Canadians in Medicine and Physiology in 1923, for no single event in the history of medicine had so dramatically changed the lives of so many people. He was also knighted in 1934. Mr. Banting was the greatest medical scientist known to mankind and this can be seen through his heroic efforts in World War One, his healing acts in life saving work, and great achievements in medicine and physiology.…
Even though there were many important discoveries relating to insulin and diabetes, there still was no cure or treatment for it. Individuals diagnosed with this disease died shortly after diagnosis. In the early 1900’s, Frederick Allen – a leading diet therapist – invented a diet specifically for diabetic patients. He called it ‘the undernutrition approach’ where as his patients called it ‘the starvation diet.’ This diet allowed the diabetic patients an intake of 800-1000 calories per day for six days and fewer calories on the seventh day. It wasn’t ideal but the goal of this diet was to prolong the life of diabetic patients until hopefully a cure was discovered. (Turner, Novo Story of Insulin - Part 1, n.d.)…
Early treatment of insulin deficient patients was feeding them fresh pancreas and pancreas extracts. Theses treatments were ineffective as the insulin was destroyed by the digestive tract. Banting was intrigued by this disease and eagerly began to search for a way to provide the body with insulin to allow sugar into cells. All cells except brain cells have insulin receptors. (Nobelprize.org)…
History has played a significant role in our daily lives and how through the unpleasant wars that bring death, one would take for granted the good can come out of it. The advancements in technology for WW1 was worth all the lives lost by the brave canadian soldiers which, in turn, was the reason for advances in technologies people use to this day and has impacted Canada significantly. Within the list of several inventions, one of the biggest ones that impacted our society is blood transfusions, which has saved many lives in Canada. Along with this, Canada was introduced with portable x-rays which provided medics a better way to help save people who have been harmed or injured whether in battle in WWI or in a car crash in the present day.…
The inventions in this paragraph are still helpful to Canadians today as they were in the 1920s these inventions include; insulin, snowmobiles, and the oven. Insulin is used to cure diabetes so that people with diabetes can live; Dr. Fredrick Banting had finally found a way to inject insulin into humans. Snowmobiles revolutionized winter transportation, and are still used today. Snowmobiles are one of the easiest ways to travel in the snow. The oven made it much easier for a stay at home mom to cook meals for the family and is still used today.…
Cuba and the United States represent opposite ends of the healthcare spectrum. Cuba has a completely state run healthcare system, where treatment is free and the idea of paying for a doctor’s visit is strange. The system is organized to emphasize community involvement and care; each area of the country has a polyclinic that provides many of the necessary primary care specialists, and within that polyclinic system, doctor and nurse teams take even more responsibility for those around them by living among their patients and ensuring that each family receives a check up at least once a year. These services, along with other key measures, such as immunization, are compulsory, and are part of the contract between the government and its citizens—if…
The American Diabetes Association attracted my attention because I can relate to diabetes, so the field I want to pursue a career in is health care management. I have a greater understanding of the seriousness and risk of diabetes and a greater appreciation of the impact and value of proper nutrition and weight management because being a diabetic myself I had to learn to take care of myself. The American Diabetes Association was founded in October 1994 to create substantially accelerate to raise major gifts to fund diabetes research. What make the American Diabetes Association unique is its ability to match a donor’s interests and dollars with extensive diabetes research projects. The American Diabetes Association is at the forefront of the fight to prevent, treat, and cure diabetes. They provide education, promote awareness, advocate on behalf of diabetes patients, and are the authoritative source in the United States. The American Diabetes Association hosts the world’s largest diabetes meeting. The association funded researcher Allison Goldfine, MD has uncovered a surprising discovery about the production of insulin, which awards her the Career…
Imagine you’re having pizza with your friends. As you reach for a second slice, you think about your needle--and then you remember you don’t have to give shots anymore. Before, you couldn’t just eat whenever you wanted; before you had Type 1 Diabetes. Everyday you had to count carbohydrates and give the correct dosage of insulin for the predicted amount of carbs you might consume. Now, an internal artificial pancreas recognizes an increase in blood sugar and automatically supplies the correct amount of insulin to your blood stream.…
Banting and Best first managed to test the extract on diabetic dogs, keeping them healthy and free of symptoms with just a few injections a day. At this point, Professor J. MecLeod managed to get his whole research team to work on the production and purification of insulin. Then, J.B Collip joined to scientific team to test the new discovery on humans.…
The global market for insulin is expected to reach USD 47.54 billion by 2020, according to a new study by Grand View Research, Inc. Growing global prevalence of type I and type II diabetes and the presence of high unmet needs in emerging markets such as India and China are expected to be two of the most significant growth drivers of this market. Moreover, increasing incidence rates of lifestyle induced diseases such as obesity and growing global geriatric population base are expected to serve the global insulin market as drivers.…