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Cardiovascular-Active Drug Overdose

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Cardiovascular-Active Drug Overdose
Drug overdoses are associated with significant morbidity and mortality. Cardiovascular-active medications are very challenging to treat in overdose situations. Intravenous lipid emulsion therapy (ILE) was first successfully used in local anesthetic systemic toxicity (LAST) in 2006. Since then there have been numerous case reports of ILE being used in other lipid soluble medication overdoses. We describe a case of a combined beta-blocker and calcium channel blocker overdose treated successfully with ILE.

A 32-year-old Caucasian female with a history of depression was brought to the emergency department after being found unresponsive at home. She had ingested 130 tablets of Carvedilol and 30 tablets of Amlodipine overnight after an argument
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