Step 1: How will you identify the “vital” cellular protein that the virus targets for degradation? (Hint: think proteomics). (3 pts.)…
Anemia is a disease state that is characterized by a reduction of hemoglobin (Hb) or volume of red blood cells (RBC’s). The reduction in Hb or RBC’s leads to diminished oxygen carrying ability of the blood. Many forms of anemia exist – the anemias discussed will be relevant to our patient, JJ, based on her signs/symptoms and past medical history (PMH). Anemia can be classified based on the appearance or size of the RBC. The size of the RBC can be determined by either calculating the mean corpuscular volume (MCV) of the RBC based on hematocrit and…
Sickle cells can clog vessels depriving tissues of oxygen. As spoken of in two articles (US News and World Report). Sickle cells have a shorter life span…
1. Sickle cell disease is a group of disorders that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. People with this disorder have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.…
Read the situation provided. Then, provide a brief description of the pathophysiology of sickle cell anemia and complete the nursing care plan by filling in the goals, outcomes, and nursing orders for the diagnoses provided in the table.…
3 Describe three ways daily life is affected for those who have sickle cell anemia.…
My client, known as 20SE03, is a four year old preschooler that lives in a two-parent household along with his younger one year old sister. His family has recently moved to North Carolina where he was recently presented with new onset of seizures and status post cerebral vascular accident (CVA). He has a history of sickle cell disease, ulcerative colitis, acute chest syndrome, and asthma.…
Sickle cell anemia is a disease where your body produces abnormally shaped red blood cells. The cells are shaped like a crescent or sickle used to cut wheat. As the sickle cell blood cells don't last as long as normal round red blood cells this then leads to anemia. The sickle cells can also get stuck in blood vessels, blocking blood flow and are unable to get oxygen around the body effectively.…
Sickle cell disease is an inherited disorder in which red blood cells are abnormally shaped. This abnormality can result in painful episodes, serious infections, chronic anaemia, and damage to body organs.…
Pathophysiology. Sickle cell disease or sickle cell anemia (often shortened to SCD or SCA) is a…
Sickle Cell Anemia, also known as Sickle Cell Disease, is a disease that causes the production of abnormal hemoglobin. The red blood cells (RBCs) carry oxygen to organs and tissues. Hemoglobin, a molecule in the RBCs, is a protein that attaches to the oxygen in the lungs and carries it to all parts of the body. Hemoglobin takes on the oxygen, and releases carbon dioxide, a process known as oxygenation. In the tissues, deoxygenation occurs where the processes is reversed, when hemoglobin releases oxygen and takes on carbon dioxide. When the RBCs are healthy, they can easily move through the tiniest blood vessels throughout the body because of their flexibility. The hemoglobin S is fragile and abnormal in Sickle Cell Anemia, and the RBCs are pointy with a shape like the alphabet letter "C" or the crescent moon. This makes the RBCs difficult to move pass through the blood vessels. The RBCs become hard, and can get stuck in blood vessels, and often clog the spleen. This causes pain, infection, and poor blood flow in patients that have Sickle Cell Anemia. The RBCs also block blood flow to organs, such as the heart, lungs, brain, etc., which can lead to stroke, damage to organs, especially the spleen, acute chest syndrome, disability, and sometimes, even death.…
INTRODUCTION: “Pain” sudden or chronic, lasting from a few hours to a few days; from a few weeks to a few months evolving from an adhesive substance in red blood cells. The “Pain” is inherited by an retriction blood flow through the body do to an abnormality in the cells. “Sickle Cell Anemia” a chronic illness discovered in 1910 by an American physician named James Bryan Herrick. Sickle Cell is more that just pain; it is a disease that is affected by abnormal blood cells that has an adhesive formation causing the natural flow to be compromised. As a result, these abnormal cells become fixed in the blood stream and not flowing to major body organs causing extreme pain and even a stroke. Why is this process painful? Have sickle cell patient become tolerant to pain or is it because some of them handle self-care management? For many years there has been a link between Sickle Cell Anemia and Pain caused by the stickiness of the blood cells. When this occurs, it decreases normal blood flow to the major organs causing strokes.(citation ). Sickle cell anemia is most common in people whose families come from Africa, South or Central America (especially Panama), Caribbean islands, Mediterranean countries (such as Turkey, Greece, and Italy), India, and Saudi Arabia. In the United States, it's estimated that sickle cell anemia affects 70,000–100,000 people, mainly African Americans. The disease occurs in about 1 out of every 500 African American births. Sickle cell anemia also affects Hispanic Americans. The disease occurs in more than 1 out of every 36,000 Hispanic American births (Citation).More than 2 million Americans have sickle cell trait. The condition occurs in about 1 in 12 African Americans. In people with sickle cell disease, approximately 50% do not survive beyond age 20 years, and most people do not live past 50 years of age (Citation)…
Bibliography: Meier, E., & Miller, J. L. (2012). Sickle Cell Disease in Children. Drugs, 72(6), 895-906.…
the supply of oxygen gets cut off. A normal blood cell lives up to 120…
with the Sickle Cell disease, and based on these studies, the longevity and quality of life of these patients have greatly improved (Wethers, 2000). It has been researched and proven that Sickle Cell Anemia…