Ch 16 17 Activity Homework Packey Key 
Activity 16.1 Is the Hereditary Material DNA or Protein?
Accumulating and Analyzing the Evidence
Build a concept map to review the evidence used to determine that DNA was the genetic material, the structure of DNA, and its mode of replicaton. Keep in mind that there are many ways to construct a concept map.
First, develop a separate concept map for each set of terms (A to F on the next page). Begin by writing each term on a separate Post-it note or sheet of paper.
Then organize each set of terms into a map that indicates how the terms are associated or related.
Draw lines between the terms and add action phrases to the lines to indicate how the terms are related.
Here is an example:
4. After you have completed each of the individual concept maps, merge or interrelate the maps to show the overall logic used to conclude that DNA (not protein) is the heredity material.
5. When you have completed the overall concept map, answer the questions.
TERMS:
Map A
Griffith
mice
S strain of Streptococcus
R strain of Streptococcus live heat-killed transformation Avery, McCarty, and MacLeod
DNA
protein
Map B
Hershey and Chase bacteria bacteriophage (phage) (only a protein and DNA)
35S
32P
Waring blender high-velocity centrifugation
Map C
Watson and Crick
X-ray crystallography
Chargaff’s rule purine structure pyrimidine structure
H bonds phosphate sugar backbone
Map D
Meselson and Stahl conservative dispersive semiconservative nucleic acid bases
14N
15N bacteria density equilibrium centrifugation replication 1. In the early to mid-1900s, there was considerable debate about whether protein or DNA was the hereditary material.
a. For what reasons did many researchers assume that protein was the genetic material?
Biologists understood that chromosomes segregated to opposite poles in mitosis and that the chromosome number was halved in meiosis. They also knew that chromosomes were made of both protein and DNA. Chemistry had revealed that proteins were made up of
Accumulating and Analyzing the Evidence
Build a concept map to review the evidence used to determine that DNA was the genetic material, the structure of DNA, and its mode of replicaton. Keep in mind that there are many ways to construct a concept map.
First, develop a separate concept map for each set of terms (A to F on the next page). Begin by writing each term on a separate Post-it note or sheet of paper.
Then organize each set of terms into a map that indicates how the terms are associated or related.
Draw lines between the terms and add action phrases to the lines to indicate how the terms are related.
Here is an example:
4. After you have completed each of the individual concept maps, merge or interrelate the maps to show the overall logic used to conclude that DNA (not protein) is the heredity material.
5. When you have completed the overall concept map, answer the questions.
TERMS:
Map A
Griffith
mice
S strain of Streptococcus
R strain of Streptococcus live heat-killed transformation Avery, McCarty, and MacLeod
DNA
protein
Map B
Hershey and Chase bacteria bacteriophage (phage) (only a protein and DNA)
35S
32P
Waring blender high-velocity centrifugation
Map C
Watson and Crick
X-ray crystallography
Chargaff’s rule purine structure pyrimidine structure
H bonds phosphate sugar backbone
Map D
Meselson and Stahl conservative dispersive semiconservative nucleic acid bases
14N
15N bacteria density equilibrium centrifugation replication 1. In the early to mid-1900s, there was considerable debate about whether protein or DNA was the hereditary material.
a. For what reasons did many researchers assume that protein was the genetic material?
Biologists understood that chromosomes segregated to opposite poles in mitosis and that the chromosome number was halved in meiosis. They also knew that chromosomes were made of both protein and DNA. Chemistry had revealed that proteins were made up of