Chemical Properties Of Risperidone Vs. Haloperidol
1.3.c Risperidone vs Haloperidol:
Evidence proves that risperidone is often more effective in the treatment of psychosis than the most commonly prescribed typical psychotic medication, haloperidol, which is included in the current list of WHO essential medications with chlorpromazine and fluphenazine. In multiple studies, risperidone is more likely than haloperidol to improve scores in the Positive and Negative Syndrome Scale (PANSS), reduces relapse rates of psychosis, improve cognitive function in schizophrenia, and improve manic symptoms in bipolar disorder (Salwan et al. 2013). Because risperidone has a different side effect profile than typical antipsychotic medications like haloperidol, it provides an essential alternative treatment for those people who cannot tolerate the older medications (Suh, Greenspan, and Choi 2006). Major psychosis may go under-treated because of …show more content…
The chemical designation is 3-[2-[4-(6-fluoro-1, 2-benzisoxazol- 3- yl)-1-piperidinyl] ethyl]-6,7,8,9-tetrahydro- 2-methyl-4H-pyrido [1,2-a]pyrimidin- 4-one. Its molecular formula is C23H27FN4O2 and its molecular weight is 410.49 (Salwan et al. 2013)
Risperidone is a white to slightly beige powder. It is practically insoluble in water, freely soluble in methylene chloride, soluble in DMSO (Dimethyl Sulfoxide) and soluble in methanol and 0.1 N HCl. Risperdal tablets are available in 0.25 mg (dark yellow), 0.5 mg (red-brown), 1 mg (white), 2 mg (orange), 3 mg (yellow), and 4 mg (green) strengths. Tablets of 0.25, 0.5, 2, 3, and 4 mg also contain talc and titanium dioxide. Risperdal is also available as a 1 mg/mL oral solution. The inactive ingredients for this solution are tartaric acid, benzoic acid, sodium hydroxide, and purified water (Gruber 2000).
1.3.e The mechanism of action of
Evidence proves that risperidone is often more effective in the treatment of psychosis than the most commonly prescribed typical psychotic medication, haloperidol, which is included in the current list of WHO essential medications with chlorpromazine and fluphenazine. In multiple studies, risperidone is more likely than haloperidol to improve scores in the Positive and Negative Syndrome Scale (PANSS), reduces relapse rates of psychosis, improve cognitive function in schizophrenia, and improve manic symptoms in bipolar disorder (Salwan et al. 2013). Because risperidone has a different side effect profile than typical antipsychotic medications like haloperidol, it provides an essential alternative treatment for those people who cannot tolerate the older medications (Suh, Greenspan, and Choi 2006). Major psychosis may go under-treated because of …show more content…
The chemical designation is 3-[2-[4-(6-fluoro-1, 2-benzisoxazol- 3- yl)-1-piperidinyl] ethyl]-6,7,8,9-tetrahydro- 2-methyl-4H-pyrido [1,2-a]pyrimidin- 4-one. Its molecular formula is C23H27FN4O2 and its molecular weight is 410.49 (Salwan et al. 2013)
Risperidone is a white to slightly beige powder. It is practically insoluble in water, freely soluble in methylene chloride, soluble in DMSO (Dimethyl Sulfoxide) and soluble in methanol and 0.1 N HCl. Risperdal tablets are available in 0.25 mg (dark yellow), 0.5 mg (red-brown), 1 mg (white), 2 mg (orange), 3 mg (yellow), and 4 mg (green) strengths. Tablets of 0.25, 0.5, 2, 3, and 4 mg also contain talc and titanium dioxide. Risperdal is also available as a 1 mg/mL oral solution. The inactive ingredients for this solution are tartaric acid, benzoic acid, sodium hydroxide, and purified water (Gruber 2000).
1.3.e The mechanism of action of