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Chemotherapy: Classifying Chemicals In Different Ways

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Chemotherapy: Classifying Chemicals In Different Ways
1. Define the term chemotherapy. Use of chemicals for therapeutic effect is called chemotherapy.

2. Why do we need to classify drugs in different ways ? It is useful for doctors because it provides them the whole range of drugs available for the treatment of a particular type of problem.

3. How are drugs classified? (a) On the basis of pharmacological effect For example, analgesics have pain killing effect. (b) On the basis of drug action It is based on the action of a drug on a particular biochemical process. For example, antihistamines inhibit the action of histamine which causes inflammation in the body. (c) On the basis of chemical structure Drugs classified in this way
…show more content…
These are called target molecules or drug targets. 4. Name the macromolecules that are chosen as drug targets. Carbohydrates, lipids, proteins and nucleic acids are chosen as drug targets.

5. Explain the term, target molecules or drug targets as used in medicinal chemistry. Drugs usually interact with biomolecules such as carbohydrates, lipids, proteins and nucleic acids. These are called target molecules or drug targets.

6. Why should not medicines be taken without consulting doctors ? (or) Sleeping pills are recommended by doctors to the patients suffering from sleeplessness but it is not advisable to take its doses without consultation with the doctor. Why ?
Most of the drugs taken in doses higher than recommended may cause harmful effect and act as poison.

7. How do drugs act as inhibitors of enzymes? i) Drugs compete with the natural substrate for their attachment on the active sites of enzymes. Such drugs are called competitive inhibitors ii) Some bind to a different site of enzyme which is called allosteric site. This changes the shape of the active site in such a way that substrate cannot recognise

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