Cholera
The infectious agent of cholera is Vibrio cholera. Cholera bacilli grow in the small intestine and produce cholera toxin, which causes host cells to secrete water and electrolytes. A person can get cholera by drinking water or eating food contaminated with Vibrio cholerae .The disease can also be transmitted by fecal contamination of water supplies, street vended foods, or eating raw or undercooked shellfish that are naturally contaminated. Cholera is treated with antibiotics; however, the most effective therapy is IV replacement of fluids and electrolytes. There is also a short term vaccine available.
Cholera most often occurs in 3rd world countries that do not have proper sanitation equipment for their drinking water. In 2010, there was an outbreak after an earthquake in Haiti damaged the water supply. The outbreak caused several hundred deaths in Asia. People who travel to areas with epidemic cholera may be exposed to the cholera bacterium. In addition, travelers may bring contaminated seafood back to the United States, which could cause a food borne outbreak. I think the culprit of this disease is poor sanitation, contaminated drinking water, poor hygiene, and lack of/inadequate sanitation equipment. In the US, there are occasional cases of cholera but very few because modern water and sewage treatment systems.