Coelomic Fuid of Earthworm-Effects
PROJECT PROPOSAL
PROJECT TITLE
Isolation of antibacterial protein from coelomic fluid of earthworm-Perionyx excavatus ( Indian blues) and elucidation of its cytotoxic effects
PROJECT PROPOSAL
3. PROJECT TITLE: “Isolation of antibacterial protein from coelomic fluid of earthworm - Perionyx excavatus ( Indian blues) and elucidation of its cytotoxic effects”
4. SPECIFIC AREA OF THE PROJECT: “ VERMITECHNOLOGY”
5. INTRODUCTION:
5.1 ORIGIN OF THE PROPOSAL:
Earthworms have long been known as Farmer’s friends because of their enormous use in agriculture. This coupled with the fact that it has been used in traditional medicine for 1000’s of years ( Prakash et al, 2008) has helped its research to reach new heights. Several drugs based on genomic approaches are in the market. Probably, earthworms are the most promising sources to combat various physiological and pathological disorders in humans. If the antibacterial protein is isolated and is proved non-cytotoxic to humans, then it can be researched and developed further as a drug for curing various diseases caused by Escherichia coli and Staphylococcus aureus ailments in human beings and thus give an impetus to further research on being used as model organisms to be studied.
5.2 DEFINITION OF THE PROBLEM:
Treating every bacterial-caused disease with antibiotics causes several side effects and in the long run antibiotic resistance towards that disease.
Hence to overcome this problem, I have chosen the protein that would be isolated from coelomic fluid of earthworm - Perionyx excavatus. This if proved non-cytotoxic to humans can be researched further on its antibacterial nature specific for Escherichia coli and Staphylococcus aureus.
5.3 SPECIFIC OBJECTIVE:
PROJECT TITLE
Isolation of antibacterial protein from coelomic fluid of earthworm-Perionyx excavatus ( Indian blues) and elucidation of its cytotoxic effects
PROJECT PROPOSAL
3. PROJECT TITLE: “Isolation of antibacterial protein from coelomic fluid of earthworm - Perionyx excavatus ( Indian blues) and elucidation of its cytotoxic effects”
4. SPECIFIC AREA OF THE PROJECT: “ VERMITECHNOLOGY”
5. INTRODUCTION:
5.1 ORIGIN OF THE PROPOSAL:
Earthworms have long been known as Farmer’s friends because of their enormous use in agriculture. This coupled with the fact that it has been used in traditional medicine for 1000’s of years ( Prakash et al, 2008) has helped its research to reach new heights. Several drugs based on genomic approaches are in the market. Probably, earthworms are the most promising sources to combat various physiological and pathological disorders in humans. If the antibacterial protein is isolated and is proved non-cytotoxic to humans, then it can be researched and developed further as a drug for curing various diseases caused by Escherichia coli and Staphylococcus aureus ailments in human beings and thus give an impetus to further research on being used as model organisms to be studied.
5.2 DEFINITION OF THE PROBLEM:
Treating every bacterial-caused disease with antibiotics causes several side effects and in the long run antibiotic resistance towards that disease.
Hence to overcome this problem, I have chosen the protein that would be isolated from coelomic fluid of earthworm - Perionyx excavatus. This if proved non-cytotoxic to humans can be researched further on its antibacterial nature specific for Escherichia coli and Staphylococcus aureus.
5.3 SPECIFIC OBJECTIVE: