University of Phoenix
HCS465
Carita Higgs
12/24/2012
Judith Curry
Introduction
This paper gives a literature review on Cognitive stimulation therapy in Alzheimer’s disease. The trial was give to determine the effectiveness of cognitive stimulation therapy in the treatment of neuropsychiatric symptoms in patients with Alzheimer’s disease. There study was given in a randomized, controlled, rater-blind clinical trial in a military sanatorium. There were thirty two patients that have mild to moderate Alzheimer’s disease that has neuropsychiatric symptoms. All patients were put into cognitive or controlled groups for up to 10 weeks. The effective measures taken include the Mini Mental State Examination and the Neuropsychiatric Inventory.
Alzheimer’s disease is a condition characterized by deterioration in multiple cognitive areas, impairment in the ability to carry out daily activities, and a number of neuropsychiatric and behavioral. An individuals with Alzheimer’s disease experience neuropsychiatric symptoms like agitation and …show more content…
disturbances during the course of their illnesses. When an individual has neuropsychiatric problems it not only affects their quality of life but also put burdens on their family members. There are previous studies that show that cognitive stimulation/training therapy along with the pharmacological medication can stabilize or improve cognitive function in mild to moderate Alzheimer’s disease patients.
Role of Literature review in this research article
The role of the literature review in this article points out the steps that was taken in the trial to assist the individuals involved to help control the depression and apathy using the cognitive stimulation process. The current study is more focused on increasing the research of cognitive stimulation on the individuals with neuropsychiatric symptoms in patients with the Alzheimer’s disease using the design of a control group. The participant that was chosen to be in the trial went through several tests to ensure they are what the researchers are looking for with the trial. This trial is very important to many individuals with the Alzheimer’s disease as well as the caretaker and family members. The qualifications for the individuals to join the trial are the individuals could not have any history of taking any antidepressant medication and had to have a score of 10-24 on the Mini Mental State Examination. There where individuals who also where excluded from the trial for many reason for example if a individual had sever hearing and visual impairments or if the individuals had any history of psychotic disorders they could not partake in the trial. Each individual was to sign the consent form. The consent form informed the individuals on the purpose of the study and the procedures that was going to take place during the study.
There was several assessment instrument used throughout the trial. The Psychopathological assessment is based on the Neuropsychiatric Inventory that was given to the caregiver 4 weeks prior to the study, the Mini Mental State Examination was given to identify decline in cognitive functioning.
The ethical consideration in data collection
The ethical consideration to take in during any trial when collecting data is the time that is put into the data collection and the expense it takes to collect data ant to analyze it. Getting the individuals that are a part of the trial written signatures of the procedures and test that are required for the trial as well as a written consent on the medications that they will be taking is ethical consideration that should be taken seriously. The consent form has everything that would be involved and taken place in the study. The participating individuals will have to volunteer to be in the study trial. Every individual in the trial was not forced to be involved in the trial. The ethical consideration that any individual that would be caused harm or that would not be a benefit to the research was not chosen to be involved. The study is used to assist individual with the Alzheimer’s disease as to their condition to get better.
What is the data telling us in terms of statistical analysis?
The statistical analysis in this research tells that in the mild to moderate Alzheimer disease patients that are on a stable dose of cholinesterase inhibitor will benefit from the cognitive stimulation therapy. Not only was there a significant affect with the cognitive stimulation therapy but also with the neuropsychiatric disturbance the results were highly significant. The trial was formed into two groups and 16 individuals were placed within the two groups. There was a period of a 10 week intervention sessions and during the session there was no dosage of psychoactive medications. There were 3 patients that withdrew from the trial, one patient from the control group and the other two from the cognitive stimulation group.
Are the findings statistically significant?
The findings in the article are significantly statistical.
The procedures, assessments and the conclusions of the trial helped the researchers get the information they needed and also the individual Alzheimer’s patients had significant assistance with their many issues that comes with having the Alzheimer’s disease. The medications and the assessments that the individuals went through helped the researchers get the data that they needed to assist them with their psychiatric issues from the affects of having the Alzheimer’s disease. The cognitive stimulation therapy have great effects apathy and depression symptoms and in the Mini Mental State Examination in patients with mild to moderate Alzheimer’s disease. The cognitive stimulation therapy should be taken as a therapeutic option for the individual patient with mild to moderate Alzheimer’s
disease.
Reference
Yi-Xuan, N., Ji-Ping, T., Jin-Qun, G., Zeng-Qiang, Z., & Lu-Ning, W. (2010). Cognitive stimulation therapy in the treatment of neuropsychiatric symptoms in Alzheimer’s disease: a randomized controlled trial. Clinical Rehabilitation, 24(12), 1102-1111. doi:10.1177/0269215510376004