Introduction:
Ultrasound is a non-ionizing, medical imaging modality that uses high-frequency sound waves and their echoes to produce images of organs and their movement in real time. A major limitation of ultrasound imaging is the often poor definition of the produced image. This poor image definition is attributed to ultrasound frequency in which there is a trade-off between spatial resolution and attenuation. This trade-off has been remedied by the introduction of contrast agents, which are typically microbubbles. Contrast-enhanced ultrasound utilizes these microbubbles in targeted or untargeted fashion depending on their intended clinical applications. This paper will explore the general features of microbubble