Araetus of Cappadocia (81-138 AD) described diabetes as the "melting down of flesh and limbs into urine" . This conclusion was drawn from the weight loss that occurred in diabetic patients due to the inability to absorb nutrients. There was more frequent urination, hence the "melting down of flesh and limbs into urine" was believed. The term Mellitus was then later added due to the sweet tasting nature of the urine. (Welbourn R B in W F Bynum & R Porter). It should be noted that circa 1550, a mathematician by the Geronimo Cardona found the volume of urine is less than the fluids consumed by a person suffering from diabetes rather than the view that more urine was produced than water consumed which was prevalent until that time.
In 164 AD, Galen, a Greek physician, misdiagnosed diabetes as a disease of the kidneys due to the excess amounts of urine produced in diabetic patients, which had seemed to be the only viable conclusion that could be drawn at that point in medical history (Welbourn R B, in W F Bynum & R Porter, 1993). As quoted in Diabetes Spectrum, 2001, "He referred to the ailment as "diarrhoea of the urine" and "the thirsty disease."".
After Galen, there was Paracelsus in the 16th