Difference Between Hemostasis And Inflammation

Hemostasis is also tightly linked to inflammation. Both systems are interrelated as part of the innate host defense mechanism and show a two-way crosstalk between each other. Inflammation induced during infection generally shifts the hemostatic mechanism toward thrombosis by up-regulation of procoagulant factors, down-regulation of anticoagulants and inhibit fibrinolytic activity. However, coagulation product such as thrombin also has a variety of activities on cells that result in augmentation of the inflammatory response. In addition, anticoagulatory molecules such as APC possess not only anticoagulatory activity, but also anti-inflammatory activity. However, infection with certain viruses can tilt the hemostasis toward bleeding and cause