Dimedone Bis Semicarbazone Case Study

CHAPTER 3
Studies on Mn (II), Co (II), Ni(II),Cu(II),Zn(II) and Cd(II) Complexes of Dimedone bis Semicarbazone (H2DSC)
During the past few decades, major developments have been achieved in the research of coordination compounds with special emphasis on metal complexes of Schiff bases containing nitrogen and oxygen donors 1-5 . This may be due to their stability, biological activity5-6and potential applications in many fields 9-10. Biological activity of complexes derived from semicarbazide has been widely studied 5 and contrasted for processes such as, antitumor, antiviral, anti malarial and anti tuberculosis activities. 5,6,7,8 We have attempted to synthesise a novel ligand dimedone bis semicarbazone and to explore its possibilities as active and potential biological agent. With the aim of further research complexes of semicarbazone of dimedone were
The Cu (II) complexes usually have a distorted octahedral stereochemistry. A few are known with square planar or approximately tetrahedral geometry. But stereochemistry has little effect on the magnetic moment of Cu (II) complexes and magnetic moment is about 1.90 BM. In regular octahedral Cu (II) complexes ground term is 2Eg and hence no orbital contribution is expected. The spin only magnetic moment value corresponding to one unpaired electron is 1.73 BM, but the observed values fall in the range 1.80-2.10 BM. The slightly higher value is due to the spin orbit coupling. In regular tetrahedral Cu (II) complex the ground term being a triplet state, orbital contribution is expected and theoretically predicted value of magnetic moment is 2.20 BM 16 . But the reported values are in the range 1.95-2 BM 17 .The observed magnetic moment values of Cu (II) complexes of H2DSC is 1.77BM which indicates octahedral geometry of the Cu (II)