Drugs & Behavior Exam Study Guide
Drugs & Behavior EXAM I Study Guide
Every correct answer is on the test…MC & Matching terms with definitions. No short answers…
Terms:
Psychopharmacology study of the action of drugs on living organisms
Specific Drug Effects: result from physical and biochemical interactions of a drug with its target tissue
Therapeutic effects- desirable effects of drug-receptor binding
Side effects- undesirable effects of drug-receptor binding
Non-specific Drug Effects: effects of a drug not based on drug-receptor interaction but due to other characteristics of the “taker” i.e. mood/expectations
Factors that influence how fast & well a drug acts:
Route of administration
Ionization
Ability to cross into CNS
Depot Binding
Biotransformation and elimination
Pharmacokinetics Factors that affect movement of a drug into, through, and out of the body
Pharmacodynamics (neuropsychopharmacology) a dynamic interaction: the study of the changes in neurons and how it changes and is influenced by behavior. Example- moods/expectations can influence the response to a drug
Bioavailability the concentration of drug present in the blood that is free to bind to specific target sites. *Pharmacokinetic factors that determine bioavailability of drugs.
Teratogens agents that induce developmental abnormalities in the fetus. The effect of teratogens such as drugs (therapeutic and illicit), exposure to X-rays, and some maternal infections are dependent on the time of exposure.
Periods of maximum sensitivity for organ systems (days after fertilization):
Brain 15-60 days
Eye 15-40 days
Genitalia 35-60 days
Heart 15-40 days
Limbs 25-35 days
First order kinetics how most drugs are removed from the blood. In an exponential fashion, a constant fraction 50% of free drug in the blood is removed during each time interval.
Half life- refers to the amount of time it takes to remove 50% of the drug in the blood
If more drug is in the body, more is removed.
Zero order
Every correct answer is on the test…MC & Matching terms with definitions. No short answers…
Terms:
Psychopharmacology study of the action of drugs on living organisms
Specific Drug Effects: result from physical and biochemical interactions of a drug with its target tissue
Therapeutic effects- desirable effects of drug-receptor binding
Side effects- undesirable effects of drug-receptor binding
Non-specific Drug Effects: effects of a drug not based on drug-receptor interaction but due to other characteristics of the “taker” i.e. mood/expectations
Factors that influence how fast & well a drug acts:
Route of administration
Ionization
Ability to cross into CNS
Depot Binding
Biotransformation and elimination
Pharmacokinetics Factors that affect movement of a drug into, through, and out of the body
Pharmacodynamics (neuropsychopharmacology) a dynamic interaction: the study of the changes in neurons and how it changes and is influenced by behavior. Example- moods/expectations can influence the response to a drug
Bioavailability the concentration of drug present in the blood that is free to bind to specific target sites. *Pharmacokinetic factors that determine bioavailability of drugs.
Teratogens agents that induce developmental abnormalities in the fetus. The effect of teratogens such as drugs (therapeutic and illicit), exposure to X-rays, and some maternal infections are dependent on the time of exposure.
Periods of maximum sensitivity for organ systems (days after fertilization):
Brain 15-60 days
Eye 15-40 days
Genitalia 35-60 days
Heart 15-40 days
Limbs 25-35 days
First order kinetics how most drugs are removed from the blood. In an exponential fashion, a constant fraction 50% of free drug in the blood is removed during each time interval.
Half life- refers to the amount of time it takes to remove 50% of the drug in the blood
If more drug is in the body, more is removed.
Zero order