Drugs Study

Generic Name | Brand Name | Classification | Mechanism of Action | Contraindication | Indication | Side Effects | Adverse Effects | Nursing Consideration | Mefenamic AcidDosage: 500 mg cap q 6 | Analmin | AnalgesicNon-SteroidalAnti-inflammatory | Mefenamic Acid has analgesic, anti-inflammatory and anti-pyretic properties. It is derivative of N-phenyl anthranili acid. Mefenamic acid shows central as well as peripheral analgesia. It is an inhibitor of cyclo-oxygenase. It also antagonizes certain effects of prostaglandins | -patients hypersensitive to the drug-patients withactive ulceration or chronic inflammation of either upper and lower gastrointestinal tract in patients with hyper pre-existing renal disease | Relief of pain including muscular, rheumatic, traumatic, dental, post-op and postpartum pain, headache and in children with fever and juvenile RA. Also for the relief of primary dysmenorrhea | Headaches Nervousness VomitingDiarrheaconstipationgas or bloatingheadachedizzinessnervousnessringing in the ears | Cardiovascular effects: Congestive heart failure, hypertension, tachycardia, syncope, arrhythmia, hypotension, myocardial infarction, palpitations, and vasculitis.GI effects: diarrhea, nausea with or without vomiting, abdominal pain, dyspepsia, heartburn, flatulence, constipation, gross bleeding/GI perforation, and peptic ulcer with or without bleeding. * Hematologic effects: decrease in hematocrit, principally in patients who have received the drug for prolonged periods. * Nervous system effects: drowsiness, dizziness, nervousness, headache, anxiety, asthenia, confusion, depression,dream abnormalities, malaise, paresthesia, somnolence, tremors, vertigo, and insomnia occur occasionally. * Ocular and otic effects: blurred vision, tinnitus, conjunctivitis, and hearing impairment. * Other adverse effects: urticaria, rash, pruritus, alopecia, photosensitivity, perspiration, asthma, dyspnea, respiratory depression, pneumonia, fever, infection, sepsis,