The Cell Cycle
Stages of the Cell Cycle:
G1 – cell growth
S – DNA replication and continued cell growth
G2 – Final preparations for division and continued cell growth
M – Mitosis or cellular replication
Some Important Terms for Replication:
Chromosome – rod-shaped body in the nucleus that is only visible during replication that contains DNA and is our hereditary unit.
Nucleolus – organelle inside the nucleus composed of RNA for ribosome formation. Spindle – microtubule structure that brings about chromosome movement during cell division.
Chromatids – two identical parts of a chromosome following DNA replication.
Centromere – site where sister chromatids are held together.
Centrosome – central microtubule-organizing center of cells.
Centriole – short cylindrical organelle in animal cells that contains microtubules and is associated with the formation of the spindle.
Spindle – a structure appearing during replication that brings an orderly distribution of chromosomes to the daughter cells.
Cytokinesis – division of the cytoplasm, usually at the conclusion of mitosis.
Homologues – chromosomes that look alike and carry genes for the same traits but are not identical.
Crossing over - exchange of genetic material between homologue chromosomes. For more information, refer to chapter 15 in your lab manual.
Stages of Mitosis
Prophase – The chromosomes within the nucleus condense. Chromosomal replication has already occurred during interphase, so each chromosome already has a sister chromatid. The mitotic spindle begins to form.
Metaphase – The sister chromatics have migrated to the center of the cell and are aligned with the mitotic spindle.
Anaphase – The centromeres split and each daughter chromosome begins moving towards a new cell. Each cell has the diploid number of chromosomes.
Telophase – Division is almost complete. New nuclear envelopes form around daughter chromosomes.
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