Effect of Vitamin E and Selenium as Immunomodulators on Induced Aflatoxicosis in Broiler Birds
Pak. j. life soc. sci. (2009), 7(1):31-34
Pakistan Journal of Life and Social Sciences
Effect of Vitamin E and Selenium as Immunomodulators on Induced Aflatoxicosis in Broiler Birds
Ab eer a M ub ar a k, As i f R as h id , I mt ia z Ah mad K h an a nd Az har H u ss ai n Vet eri n ar y Re sea r c h I n s tit u te, G ha zi Ro ad La ho re Ca nt t -P a ki s ta n Abstract Mycotoxicosis, a serious problem to commercial poultry, is incurable; however certain group B vitamins, vitamin E and selenium are capable of reducing and facilitating the decomposition and detoxification of mycotoxin within the body. In present study, effect of vitamin E and selenium was studied in broiler birds with induced aflatoxicosis. Five groups of broilers birds were reared and feed differently i.e., Group B was fed with vitamin E and selenium along with aflatoxin B1 mixed feed, group C was fed with vitamin E and aflatoxin B1 mixed feed, group D was fed with selenium and aflatoxin B1 mixed feed and group E was fed only aflatoxin B1 mixed feed while group A was kept as control. The study was conducted for three weeks and concluded that vitamin E and selenium in combination can act as immunomodulator even then the birds were challenged with aflatoxin B1. Keywords: Mycotoxicosis, vitamin E, selenium immunmodulator Introduction Mycotoxins are the metabolic products of toxigenic fungi, released during the growth in various feedstuffs. Aflatoxins are the most common mycotoxins, widely prevalent in different feed commodities. These toxins are considered to be most important because of wide range of host susceptibility, immunosuppression, hepatotoxicity and heat stable properties of aflatoxin and are potential hazards affecting the poultry industry resulting in heavy economic losses (Mundas and Rao, 2001). Aflatoxins are proved to suppress the immune response of the birds leading to persistence of Newcastle disease in broiler flock even after vaccination (Mani et al., 2001). Various findings
Pakistan Journal of Life and Social Sciences
Effect of Vitamin E and Selenium as Immunomodulators on Induced Aflatoxicosis in Broiler Birds
Ab eer a M ub ar a k, As i f R as h id , I mt ia z Ah mad K h an a nd Az har H u ss ai n Vet eri n ar y Re sea r c h I n s tit u te, G ha zi Ro ad La ho re Ca nt t -P a ki s ta n Abstract Mycotoxicosis, a serious problem to commercial poultry, is incurable; however certain group B vitamins, vitamin E and selenium are capable of reducing and facilitating the decomposition and detoxification of mycotoxin within the body. In present study, effect of vitamin E and selenium was studied in broiler birds with induced aflatoxicosis. Five groups of broilers birds were reared and feed differently i.e., Group B was fed with vitamin E and selenium along with aflatoxin B1 mixed feed, group C was fed with vitamin E and aflatoxin B1 mixed feed, group D was fed with selenium and aflatoxin B1 mixed feed and group E was fed only aflatoxin B1 mixed feed while group A was kept as control. The study was conducted for three weeks and concluded that vitamin E and selenium in combination can act as immunomodulator even then the birds were challenged with aflatoxin B1. Keywords: Mycotoxicosis, vitamin E, selenium immunmodulator Introduction Mycotoxins are the metabolic products of toxigenic fungi, released during the growth in various feedstuffs. Aflatoxins are the most common mycotoxins, widely prevalent in different feed commodities. These toxins are considered to be most important because of wide range of host susceptibility, immunosuppression, hepatotoxicity and heat stable properties of aflatoxin and are potential hazards affecting the poultry industry resulting in heavy economic losses (Mundas and Rao, 2001). Aflatoxins are proved to suppress the immune response of the birds leading to persistence of Newcastle disease in broiler flock even after vaccination (Mani et al., 2001). Various findings
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