The witches prophecies led to macbeth's desire for power,which leads to his death.
We can see this when the witches say (1.3.14) “All hail Macbeth hail to thee throne of glains” In this quote we can see that the witches are worshipping Macbeth because they know that he will become the king this will also fuel macbeth's ambition to be king making him do anything for it.
(4.1.83) “Be bloody bold and resolute laugh to scorn the power of man for none of woman born shall harm Macbeth. We can see here later in the book the witches messing with Macbeth giving the false sense of hope making him feel powerful thinking that he can destroy