Review of Related Literature and Studies
This chapter provides an overview of the topics and researches that are related with the Anthelmintic property of Flavonoids from leaves of Spinach (Spinacia oleracea) against Ascaris suum, the disease, the constituent used, the plant, and related reliable published works. The World Health Organization - Representative Office in the Philippines stated in one of their articles that the Philippines is endemic of soil-transmitted helminthiases (STH), also known as intestinal worm infections are the diseases that are most common among school-age children (wrpo.who.int, 2016). Ascariasis refers to the infection with Ascaris lumbricoides, which is particularly common in children. The pathology …show more content…
Flavonols are found in spinach with its prominent food flavonoids such as Myricetin, Quercetin and Kaempferol. Most flavonoids are commonly concentrated in leafy vegetables or the skin and peels of a certain fruit. It has an aromatic chromophores that in nature, it is in colorful pigments of vegetable plants that attract pollinating insects and assist in propagation. And it also serves as phytoalexins which acts as antimicrobial compound (Corcoran, McKay, et. al., 2012). A lot of studies show that a regular intake of foods with flavonoids may reduce the risk of several chronic conditions such as the neurodegenerative diseases, atherosclerosis and other types of cancer. These researches contain considerable interest in flavonoids as it is associated to a positive health outcomes. (Corcoran, McKay, et. al., …show more content…
It has associated benefits in health especially the heart. (Erdman, Balentine, et. al., 2013). The top sources of flavonoids include such as fruits, nuts and vegetables and beverages. It shows that an intake of spinach(raw) which is one of the abundant sources of flavonoids has a main component of flavanols with an equal mg/serving at 33.6-288.4. (Corcoran, McKay, et. al., 2012) Flavonoids are used to be as a antioxidant, cell cylcing, cell prolification, and inflammation. It induces Phase II antioxidant and detoxification eznymes such as glutathione, NAD(P)H and epoxidanse hydrolases. (Zhang and Gordon, 2014) Researches show that plants containing organic natural substances that have flavonoids have an anthelmintic effect. And compared to three leading medicines in the marsuch as Mebendazole, Albendazole and Decaris. (Bahizire, Bagalwa, et. al.,