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Genetic Disease Project

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Genetic Disease Project
Tumor Protein P53

1. There is no particular group that is affected by this disease and there is no geographic prevalence to this disease. 400 people have this disease in the United States.

2. There are many different names for this protein such as,
Antigen NY-CO-13
Cellular tumor antigen p53
P53_HUMAN
P53 Tumor Suppressor
Phosphoprotein p53
Transformation-related protein 53; TRP53
TRP53
Tumor protein p53(Li-Fraumeni syndrome)

3. the symptoms of this disease are cancer at a young age (under 45), and multiple instances of cancer in one life time. These are all genetic due to a family members or close relative having this disease as well.

4.Tumor protein p53 acts as a tumor suppressor it prevents tumor from forming. It does this by making sure cells don't divide too fast. p53 would lead to DNA repair or tell the cell to kill itself.

Work cited

1.http://ghr.nlm.nih.gov/condition/li-fraumeni-syndrome

2. http://ghr.nlm.nih.gov/gene/TP53

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