Biology and Society: Crime Scene Investigations: Murders in a Small Town
On November 22,1983
- A 15-year-old girl was raped and murdered on a quiet country lane.
- Three years later, another 15-year-old girl was raped and murdered.
DNA fingerprinting of DNA samples from suspects and the crime scene
- Proved one man guilty and another man innocent.
Recombinant DNA Technology
Recombinant DNA technology is a set of techniques for combining genes from different sources into a single DNA molecule. (Figure 1)
- An organism that carries recombinant DNA is called a genetically modified (GM) organism.
Recombinant DNA technology is applied in the field of biotechnology.
- Biotechnology uses various organisms to perform practical tasks
From Humulin To Genetically Modified Foods
By transferring the gene for a desired protein product into a bacterium, proteins can be produced in large quantities.
Making Humulin
In 1982, the world’s first genetically engineered pharmaceutical product was produced.
- Humulin, human insulin, was produced by genetically modified bacteria.
Humulin was the first recombinant DNA drug approved by the FDA.
DNA technology is also helping medical researchers develop vaccines.
-A vaccine is a harmless variant or derivative of a pathogen.
- Vaccines are used to prevent infectious diseases.
Genetically Modified (GM) Foods
Today, DNA technology is quickly replacing traditional plant-breeding programs.
Corn has been genetically modified to resist insect infestation.
-This corn has been damaged by the European corn borer. (Figure 3)
“Golden rice” has been genetically modified to contain beta-carotene. (Figure 4)
- Our bodies use beta-carotene to make vitamin A.
Farm Animals and “Pharm” Animals
While transgenic plants are used today as commercial products, transgenic whole animals are currently only in the testing phase.
These transgenic sheep carry a gene for a human blood protein. (Figure 5)