gold nano particles
Gold Nanoparticles for Diagnosis and Treatment of Cancer
Abstract—Nanotechnology has been an extremely hot topic over the decade. It is the science, engineering and technology conducted at nanoscale. Two of the main applications of nanotechnology include material science and biomedicine. We have achieved great strides in applying nanotechnology to material science that is well justified by the decreasing size of electronics available in market. However we haven’t made a mark in biomedicine yet. In 1971, US President Richard Nixon and Congress declared war on cancer. Since then a large amount of research has been carried out towards diagnosis and treatment of cancer. We now have better detection methods that bring about cheaper, faster and less invasive cancer diagnoses. Post diagnosis there is still the prospect of surgery, radiation treatment or chemotherapy, all of which have serious side effects. In this review paper, we focus our attention towards gold nano–particles and their biomedical application in targeting cancer. Different types of gold nano-particles will be discussed and how they are used for in-vitro assays, in-vivo and ex-vivo imaging, cancer therapy and drug delivery. The key feature of nano-particles is multifunctionality. These particles have many properties that are attractive for use in cancer therapy and thus there is huge potential of using nano-particles for cancer therapy.
Keywords—nanoscale; gold nanoparticles; cancer; multi-functionality; optical imaging
I. INTRODUCTION
Nanotechnology means the study of scientific objects at sub atomic level. Tremendous advancements in this field, has led to the discovery of a range of nano structures which posses immensely important properties for various chemical, biological and biomedical applications. Various classes of nanostructures relevant to the above mentioned fields include semiconductor quantum dots, magnetic nano- particles, polymeric particles, carbon-based nanostructures and
Abstract—Nanotechnology has been an extremely hot topic over the decade. It is the science, engineering and technology conducted at nanoscale. Two of the main applications of nanotechnology include material science and biomedicine. We have achieved great strides in applying nanotechnology to material science that is well justified by the decreasing size of electronics available in market. However we haven’t made a mark in biomedicine yet. In 1971, US President Richard Nixon and Congress declared war on cancer. Since then a large amount of research has been carried out towards diagnosis and treatment of cancer. We now have better detection methods that bring about cheaper, faster and less invasive cancer diagnoses. Post diagnosis there is still the prospect of surgery, radiation treatment or chemotherapy, all of which have serious side effects. In this review paper, we focus our attention towards gold nano–particles and their biomedical application in targeting cancer. Different types of gold nano-particles will be discussed and how they are used for in-vitro assays, in-vivo and ex-vivo imaging, cancer therapy and drug delivery. The key feature of nano-particles is multifunctionality. These particles have many properties that are attractive for use in cancer therapy and thus there is huge potential of using nano-particles for cancer therapy.
Keywords—nanoscale; gold nanoparticles; cancer; multi-functionality; optical imaging
I. INTRODUCTION
Nanotechnology means the study of scientific objects at sub atomic level. Tremendous advancements in this field, has led to the discovery of a range of nano structures which posses immensely important properties for various chemical, biological and biomedical applications. Various classes of nanostructures relevant to the above mentioned fields include semiconductor quantum dots, magnetic nano- particles, polymeric particles, carbon-based nanostructures and
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