Student ID: 00000003327 Patient’s RN: HTJ396999
Date of clerking: 31/4/2017 Date of admission: 31/4/2017
An 8 years old Malay boy was presented to the Emergency Department with pain and bleeding on the right leg for 1 day. It was preceded by a fall while he was climbing a slippery stairs at school where he landed on his right leg. After the fall, he started to experience pain and noticed a bleeding wound on his right leg. He was able to ambulate and there was no loss of consciousness, retrograde amnesia, nausea, vomiting or any sign of other significant injury. Other than that, he does not have any significant illnesses. He is currently living with his family. He was alert and responsive. …show more content…
Cefuroxime: 2nd generation Cephalosporin.
The cephalosporins are broad-spectrum antibiotics which are used for the treatment of septicaemia, pneumonia, meningitis, biliary-tract infections, peritonitis, and urinary tract infections. The pharmacology of the cephalosporins is similar to that of the penicillins, excretion being principally renal.
The principal side-effect of the cephalosporins is hypersensitivity and about 0.5–6.5% of penicillin-sensitive patients will also be allergic to the cephalosporins. If a cephalosporin is essential in patients with a history of immediate hypersensitivity to penicillin, because a suitable alternative antibacterial is not available, then cefixime, cefotaxime, ceftazidime, ceftriaxone, or cefuroxime can be used with caution. Cefuroxime axetil, an ester of the ‘second generation’ cephalosporin cefuroxime, has the same antibacterial spectrum as the parent compound; it is poorly absorbed and needs to be given with food to maximise absorption.
Cefuroxime is a ‘second generation’ cephalosporin that is less susceptible than the earlier cephalosporins to inactivation by beta-lactamases. It is, therefore, active against certain bacteria which are resistant to the other drugs and has greater activity against Haemophilus