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Hot Zone
10. Standards/Physiology: Organisms have a variety of mechanisms to combat disease. As a basis for under-standing the human immune response: d. Students know there are important differences between bacteria and viruses with respect to their requirements for growth and replication, the body's primary defenses against bacterial and viral infections, and effective treatments of these infections. 1. Vaccines- used against viruses before they enter the body. 2. Antibiotics- used against bacteria with onset of infection.

Vocabulary; lethal- refers to anything dangerous enough to cause death nonlethal- not likely to kill or cause great bodily injury contagion- Disease transmission by direct or indirect contact microbes- a microorganism, especially a bacterium that causes disease antibiotics- agent that destroys bacteria: a naturally produced substance that kills or inactivates bacteria, but has no effect against viruses. vaccine- a preparation containing weakened or dead microbes of the kind that cause a disease, administered to stimulate the immune system to produce antibodies against that disease, before contact. sputum- throw-up, vomit, oral discharge adrenaline- A hormone secreted by the medulla of the adrenal gland, especially in times of stress or injury.
Chapter 1: Something In The Forest 1. Who is Charles Monet? 2. What happens to Monet? 3. (pages 4-6) The author uses a sensory image of hot and cold in describing the case. Why? 4. The author makes a distinction between lethal and nonlethal contagion. What is the difference? 5. Why were workers burning the fields? What impact does this have on the migration of microbes and the natural biodiversity of an area? 6. Why is salt so “precious” in the rainforest? 7. (Page 13) List three possible sources of infection from the cave. 1. 2. 3. 8. Why do you think the author uses a reference about the pull of the cave” being like gravity”? 9. Why don’t antibiotics work on viruses? 10. How does the ease of plane travel make us more susceptible to infection? 11. (Page 18) How could you mix up a bag of the black sputum “vomito negro”? 12. Monet vomits even though his stomach is empty. What does this tell you? 13. What is the reference to “hot” in this sequence? 14. Why is he not feeling pain at this point? 15. Is the agent that killed Charles Monet a “character” in The Hot Zone? What sort of a character is it and what role does it seem to play (lead role, villain, etc…)? The Hot Zone inspired the movie

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