INTRODUCTION
Tuberculosis has been present in human since antiquity. The earliest unambiguous detection of M. Tuberculosis involves evidence of the disease in the remains of bison in Wyoming dated to around 17,000 years ago. However, whether tuberculosis originated in bovines, and then was transferred to humans, or whether it diverged from a common ancestor, is currently unclear. A comparison of the genes of M. Tuberculosis complex (MTBC) in humans to MTBC in animals suggests humans did not acquire MTBC from animals during animal domestication, as was previously believed.
Tuberculosis, MTB, or TB, in the past also called phthisis, phthisis pulmonalis, or consumption, is a widespread, and in many cases fatal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis typically attacks the lungs, but can also affect other parts of the body. It is spread through the air when people who have an active TB infection cough, sneeze, or otherwise transmit respiratory fluids through the air. Most infections do not have symptoms, known as latent tuberculosis. About one in ten latent infections eventually progresses to active disease which, if left untreated, kills more than 50% of those so infected. Tuberculosis has two main types, active and latent tuberculosis. This was proven by many specialized doctors all over the world. In 1689, Dr. Ricin established the pulmonary form associated with tubercles as pathology, due to the variety of its symptoms. TB was not identified as a single disease until the 1820s. It was named tuberculosis until 1839, by J.L. Schonlein.