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Nutritional Control of Reproductive Status in Honeybees via DNA Methylation R. Kucharski, et al. Science 319, 1827 (2008); DOI: 10.1126/science.1153069 The following resources related to this article are available online at www.sciencemag.org (this information is current as of October 6, 2008 ):
Updated information and services, including high-resolution figures, can be found in the online version of this article at: http://www.sciencemag.org/cgi/content/full/319/5871/1827 Downloaded from www.sciencemag.org on October 6, 2008 Supporting Online Material can be found at: http://www.sciencemag.org/cgi/content/full/1153069/DC1 This article cites 25 articles, 5 of which can be accessed for free: http://www.sciencemag.org/cgi/content/full/319/5871/1827#otherarticles This article has been cited by 2 article(s) on the ISI Web of Science. This article appears in the following subject collections: Molecular Biology http://www.sciencemag.org/cgi/collection/molec_biol Information about obtaining reprints of this article or about obtaining permission to reproduce this article in whole or in part can be found at: http://www.sciencemag.org/about/permissions.dtl

Science (print ISSN 0036-8075; online ISSN 1095-9203) is published weekly, except the last week in December, by the American Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005. Copyright 2008 by the American Association for the Advancement of Science; all rights reserved. The title Science is a registered trademark of AAAS.

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Nutritional Control of Reproductive Status in Honeybees via DNA Methylation
R. Kucharski,* J. Maleszka,* S. Foret, R. Maleszka† Fertile queens and sterile workers are alternative forms of the adult female honeybee that develop from genetically identical larvae following differential feeding with royal jelly. We show that silencing the expression of DNA methyltransferase Dnmt3, a key driver of epigenetic global reprogramming, in newly hatched



References: www.sciencemag.org Downloaded from www.sciencemag.org on October 6, 2008

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