• Women are more prone 1.8 times to have knee OA than men.
• Evidences also supports a strong genetic tendency of OA (one of the studies has shown a prevalence of 39-65% of OA due to genetic predisposition)
• Overweight adults shows a high inclination towards knee OA. For every 5-kg gain in weight increases the risk of developing knee OA by 35%
Furthermore, sedentary life style, occupational and leisure activities, participation in sports that involves excessive joint loading of cartilage also may put the person at risk of OA.21