Remote Control of Fed-Batch Fermentation Systems
Eric Moreau3, Floyd Inman, III1, Sunita Singh2, Heather Walters1 and Leonard Holmes1*
1. Biotechnology Research and Training Center, University of North Carolina at Pembroke, Pembroke, NC, USA
2. Central Institute of Agricultural Engineering, Bhopal, Madhya Pradesh, India
3.Université de Picardie Jules Verne, Amiens, France
Received: June 14, 2011 / Accepted: July 11, 2011 / Published: October 10, 2011.
Abstract: Bioreactor operation requires continuous monitoring of fermentation parameters and real-time control over bioreactor devices. Remote monitoring and control of the bioreactor’s computer via the Internet avoids the necessity of personnel being continually onsite during operation. A two liter Sartorius-stedim Biostat® A Plus fermentation system was networked and interfaced with the commercial software from GoToMyPC® to allow remote control of the fermentation system utilizing the internet. The fermentation vessel was equipped with hardware calibrated for monitoring and controlling culture parameters during experimentations.
The uniform resource locator controlled night-vision web camera allowed continuous monitoring of the glass fermentation vessel during the day and at night. The main window screen of the laboratory computer can be securely accessed from any portable device (i.e. laptop) capable of establishing an Internet connection and executing the commercial software from GoToMyPC®. The secured internet protocol address, provided by GoToMyPC®, assures that the system can only be controlled by authorized users who have been given access to the account. This interface permits the remote control of the Biostat® A Plus fermentation system and possibly other automated or potentially automated culturing systems at the convenience of the user(s).
Key words: Fermentation, Fed-batch, Remote-monitoring, Remote-controlled fermentation systems.
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References: Eng. 2002, 24, 273-279. Fed-Batch Fermentation. Biotechnol. Bioeng. 2001, 74, 125-135. GmbH, 2009.