October 8, 1999 - Laila "She Bee Stingin’ " Ali (5'10", 166 lbs) made her ring debut at 21 years old against April Fowler of Michigan City, Indiana, at the Turning Stone Casino Convention Center on the Oneida Indian Nation in Verona, New York. Laila made fast work of Fowler, as she knocked her out in 31 seconds.
November 10, 1999 – Laila won her second professional bout against Shadina Pennybaker by TKO with 3 seconds left in the match. The fight occurred at the Mountaineer Race Track in Chester, West Virginia. Pennybaker was making her own pro debut after going 2-1 as an amateur. Laila bloodied Pennybaker’s lip and forced a standing eight count in the fourth when she knocked Pennybaker’s mouthpiece out. A flurry of left-right combinations sent Pennybaker reeling into a corner and produced a stoppage of the fight.
December 10, 1999 – Laila again won by TKO, this time in the second round over 6’3” Nicolyn Armstrong, at the Cobo Center Riverfront Ballroom in Detroit, Michigan. Laila knocked Armstrong down late in the first round with a jab, followed by three hard rights. In the second round, Laila battered Armstrong in a corner then knocked her flat on her back. Referee Sam Williams stopped the bout immediately, awarding Laila the knockout.
March 7, 2000 – Laila (160 lbs) moved to 4-0 with 4 KO’s by knocking out Crystal Arcand (169 lbs) of St. Paul, Alberta, Canada at 1:10 in the first round at Casino Windsor in Windsor, Ontario, Canada. Arcand, a former Tough woman competitor, was making her pro debut after going 5-0 in amateur action. Arcand came out swinging wildly, but Laila circled and landed a jab-uppercut combination that sent Arcand to the canvas after just 15 seconds. Arcand got up and Laila continued the attack, putting Arcand on the canvas again with a straight right to the head. Arcand got up to one knee but no further as she was counted out just 70 seconds into the bout.
April 8, 2000 – at the Joe Louis Arena in Detroit, Michigan,