Lipodystrophy: Effects Of Diabetes On The Body

As diabetes is one of the most common disease in the world, as of current, many health professionals have sought to figure out an alternative to the insulin treatment, because of its worsening effects on the body, such as heart stroke or liver malfunction. With the recent development in the treatment of lipodystrophy by Dr Garg, it is almost certain that this revolutionary treatment method would benefit society from a health perspective as well as an economic one. Lipodystrophy is a disease in which the body lacks leptin, a hormone made by fat cells and regulates its usage. The treatment is the injection of metreleptin, which is only prescribed for two times per life, and is more healthier and versatile usage of the drug in multiple areas:
controlled insulin resistance, lowered triglyceride levels of lipodystrophy patients and decreased fat accumulation in the liver. Although the professionals at UT Southwestern have done many clinical trials, with young women, I believe that the drug could do more to benefit the rehabilitation process as well as provide an alternate solution or possibly be prescribed for the usage of curing diabetes.
As metreleptin mainly targets the liver and the processes it conducts in order to store fat, it may be beneficial in utilizing it to assist in recovering the liver of alcoholics in rehabilitation. Generally, with an alcoholic liver, cirrhosis occurs, the rupture of the liver tissue and creation of scars under the surface due to inflammation. The same process occurs with a fatty liver, when the excess fat causes a rupture to the organ. WIth the usage of the metreleptin, it would be beneficial for the doctors and patients to recover more rapidly as the drug may benefit in the recovery of scar tissue as well as remove excess fat for the liver to impede further rupture. Likewise, the drug could benefit the pancreas during rehabilitation. Because of alcohol, cocaine, heroin and any other prescription drug abuse, the pancreas stop making digestive enzymes, therefore creating an environment to increased blood sugar and pressure. For a possible remedy, doctors may want to consider using it in rehab as it may decrease the effect the drugs may have created on the patient.
Adding on to the increased blood sugar in the body, the usage of the metreleptin might, alone, be able to control the effects of diabetes on the body, and, as demonstrated in the studies by Dr.
Garg, will provide a more stable and secure form of treatment for a diabetic. As a patient would only need be prescribed twice in their lifetime, there would be less dependency on taking medication as well as reducing blood sugar and possibly keeping the system alive and running. Metreleptin not only helps the liver, but also the pancreas in metabolic processes, so it would also be helpful to use it if a person were having a low metabolism, and are facing severe health issues due to it, such as obesity, heart disease and reproductive issues. This does not mean that everyone with low metabolism should be prescribed with this drug, because there could be an extreme imbalance in insulin or fat levels in the body. For example, if a person who is just above the normal weight and has not incurred any major injuries or procedures regarding their health as a result of low metabolism, the most effective method in which a doctor can treat them is to heavily encourage to exercise. On the other hand, if a young female came into the hospital on multiple occasions as a result of ovarian torsions as well as having a record of attempting exercise and diet, then a doctor should, at least, consider the drug to help the woman and her weight issues that came from low
metabolism.
Obviously, there would be risks in utilizing this drug, as there always is when using prescription drugs. Some may say that the drug may have an overpowering effect on the body, such as completely clearing the fat in the liver or increasing insulin levels above the homeostatic range. However, in my opinion, this is one of those situations when the advantages overpower the possible disadvantages of the usage. Overall, I believe that, as it is a new technology, there is much place for improvement and development, but with the proper trials and creativity, there is a high probability for the most dangerous diseases such as diabetes to find a closer cure than what society has now.