Macbeth and Banquo are homeward bound from battle when Macbeth is confronted by the three Witches for the first time. The three Witches present Macbeth and Banquo with prophecies. Whereas Banquo dismisses the witches as "instruments of darkness that tell us truths, win us with honest trifles, to betray's in deepest consequence—" (Act I, Scene III, Line 124), Macbeth readily ponders their words and initializes his certain fate. Macbeth's eager acceptance of the Witches' words foreshadows his darkened decisions in the future.
The regicide plot contrived by Lady Macbeth at first concerns Macbeth: "He's here in double trust: first, as I am his kinsman and his subject, strong both against the deed; then, as his host, who should against his murderer shut the door—" (Act I, Scene VII, Line 12). Through challenging Macbeth's manhood, however, Lady Macbeth is able to persuade Macbeth to commit the murder. This ability to be persuaded is a key component of Macbeth's degradation, falling deeper and deeper into the clutches of greed and immorality as he thirsts for power and security along with it.
Macbeth is greatly remorseful after the murder of Duncan, revealing his emotions to Lady Macbeth: "Will all great Neptune's ocean wash this blood clean from my hand? No, this my hand will rather the multitudinous sea incarnadine. making the green one red." (Act II Scene II Line 64). Lady Macbeth is short in her responses with Macbeth in this scene, and her words are clear and sharp: "My hands are of your color, but I shame to wear