The agreement states Pharmagen will receive up to $500 million funding for R&D costs as they are incurred solely for the research efforts of a potential new drug “X”…
The Opportunity: Merck, a global, research-driven pharmaceutical company, has core values invested in cutting edge science programs. Recently the organization was accosted by Kappa Labs with a proposal to purchase the product KL-798. This drug is associated with obesity and weight-loss which is becoming a valuable investment to the pharmaceutical industry.…
Direct Drugs Inc. (Direct) has created a plan for the acquisition of SolvGen Inc. (SolvGen), which is a publicly owned company. Direct has engaged an audit team to review agreement and procedures dealing with two separate material agreements. The first agreement is a research and development agreement and the second is a licensing and distribution agreement. The contract states that SolvGen entered into a five year research and development agreement with Careway Pharma Inc. on January 1, 2010. The agreement states that SolvGen will use its best efforts to develop a proprietary instrument system. They are expected to be ready for launch in the near future. SolvGen and Careway also entered in an agreement for a five year license and distribution. This agreement was entered in on January 1, 2010 as well. The terms of the research and development agreement state that SolvGen holds all intellectual rights that correspond with the research and development of the contract. Also with this agreement SolvGen is entitled to nonrefundable milestone payments from Careway and they are as follows:…
1. Why does Merck want to switch Pepcid to OTC status when the patent is good for another six years? How attractive is this opportunity?…
Enabling mighty competition between commonplace drug treatments and patent-expired fashioned brands is relevant to decreasing pharmaceutical charges and stimulating innovation. However, this mentioned, there are numerous troubling problems surrounding general medicines because of the convenient access to an abundance of illegal generics on the internet breaking the patent ownership and the unregulated companies that produce and supply them. At the same time familiar medicines will have to be approved identical types of depended on drugs, providing the equal fine, safety and efficacy because the normal, that is commonly no longer the case. A conventional drug must endure strict scrutiny before it is licensed and given market approval with the aid of countrywide medicines authorities. In brief, common medicines will have to comply with the same strict standards of great, safety and efficacy as usual pharmaceutical…
Another factor is that Pharmagen is also partially financing the research and development for product “X”. Plus, they had already started the research and development process prior to the contract agreement, and therefore, the success or failure of this product can have a great impact on this Pharmagen.…
First, note that the $170 million spent are sunk costs, they will be lost regardless of the decision. The relevant question is whether the incremental benefits (the present value of the profits generated from the drug) exceed the incremental costs (the $30 million needed to keep the project alive). Since these costs and benefits span time, it is appropriate to compute the net present value. Here, the net present value of DAS’s R&D initiative is $26,557,759.86…
This situation is an opportunity because Bristol-Myers needed to figure out how to successfully price and promote Datril as it launched in the analgesics market. Two main options are available (1) whether to promote Datril as a direct point of sale towards the consumer or (2) to adopt the traditional and more conservative route as that of Tylenol and promote Datril towards the trade only. Ultimately, to establish a price point that allows Datril to compete with Tylenol given like functionality.…
Create a decision tree for Merck. The 2 leftmost branches would identify the alternatives related to licensing Davarink (specifically license versus not to license). Next, if Merck decides to pursue license, they go into phase I which results in a success, or failure. Phase I success is followed by phase II where Merck has the opportunity to develop the drug to treat depression alone, weight loss alone, or both, or contemplate phase II failure. Finally phase II success for different options leads to phase III, and there are success or failure related outcomes for each of the alternatives in phase II (i.e. developing the drug to treat depression, weight loss, or both).…
While Kenneth Frazier worked liability suits for Merck, he caught the company’s attention and they hired him in 1992. By 1999 Frazier was appointed Merck’s general counsel. Merck saw that Frazier had several good personality traits and values that would benefit their organization.…
Based on the decision tree model, it is recommended that Pat Harlow does not invest in the purchase of KL-798 from Kappa Labs assuming that the current payoffs and expected probabilities given currently are correct and do not change in the future. At the current decision point, during Phase I tests, there is an expected payoff of -$1.16 million based on the probabilities of success further in the future and expected returns. If Merck can negotiate either the price of KL-798 down by more than $1.16 million or reduce their contribution to complete Phase I testing, this could be an attractive option to invest in.…
The regulatory and legal issues related to drug and pharmaceutical development and sale is very complex. In order for the FDA to approve this drug for sale it must go through a very long lengthy process of it being approved. This long process can be costly and is considered highly risky. To achieve the point where you can sell your drug, the drug company must go through drug discover and testing. This is when thousands of scientists are employed to test the drug and do clinical testing. Once you pass the rigorous process of the FDA guidelines, your drug will then go through post approval safety and marketing. During this process, safety monitoring becomes a big issue. Next is labeling, advertising and promotional claims. Legal issues can occur during clinical testing to when the drug is out for the public to use.…
Sauer, C., & Sauer, R. M. (2007, October). Is It Possible to Have Cheaper Drugs and Preserve the Incentive to Innovate? The Benefits of Privatizing the Drug Approval Process. Journal of Technology Transfer, 32(5), 509-524. doi:http://dx.doi.org/10.1007/s10961-007-9036-0…
Today’s finance is challenging in the medical environment. Cost seems to be of central concern to decision makers. This could lead you to wonder if research and development can flourish. To develop a new medication is costly and the payoff might appear in jeopardy to those that invest. Recently a new ground breaking drug called Sugammadex has been approved for use in over 40 countries around the world but further delayed in the U.S.…
This should be maintained for this deal as well. Hence the most Merck could pay as licensing fee is = 37.84%…