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Metformin Case Summary

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Metformin Case Summary
Arnold, our 48-year-old Hispanic male patient, has shown some improvement in his fasting blood glucose (FBG) level and hemoglobin A1c (HbA1c) level with metformin monotherapy. However, we would like to see his FBG at less than 110 mg/dl and his HbA1c at less than 7%. Due to this patient’s desire to only take a single medication and his refusal to alter his lifestyle, we have decided to start Arnold on Xigduo XR (dapagliflozin/metformin) 10mg/2000mg once daily, taken in the morning with food. It is recommended that the dose is increased gradually due to the gastrointestinal (GI) side effects of metformin. However, Arnold is already tolerating metformin 2000mg daily. In clinical trials, combination therapy of dapagliflozin/metformin resulted
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