1) Health and Safety at Work Act, COSHH, the Medicines Act, the Misuse of Drugs Act, the Health and Social Care Act (Regulated Activities) and the Essential Standards, the RPS Handling Medicines in Social Care Guidelines. 2)
Paracetamol – Side effects of paracetamol are rare but can include: • A rash • hypotension (low blood pressure) when given in hospital by infusion (a continuous drip of medicine into a vein in your arm) • liver and kidney damage, when taken at higher-than-recommended doses (overdose)
Simvastatin can have side effects, although not everybody will have them. For the most part side effects have been mild and short lived. The following side effects were reported rarely (1 to 10 users in 10,000).
• Anaemia,
• Stomach upsets (such as sickness, constipation, abdominal pain, flatulence, nausea, indigestion, diarrhoea, vomiting),
• Inflammation of the pancreas (severe abdominal pain radiating to the back, nausea and vomiting),
• Headache, dizziness, weakness, numbness or loss of sensation in the arms and legs,
• Hair loss, rash, itchiness,
• Muscle aches and pains, tenderness, weakness or cramps, dark coloured urine, pale coloured stools (see below and section 2).
• Liver disease (possibly presenting as yellowing of the eyes and/or skin), liver failure (very rare),
• Increase in blood levels of liver enzymes,
• An allergic reaction that may include some of the following symptoms: sudden swelling of face, tongue or throat (angio oedema, see below), a certain skin disease (lupus-like syndrome) with rash, fever and joint pain, joint and blood vessel inflammation, high levels of white blood cells, (eosinophilia), joint pains, unusual bruising, skin eruptions, swelling, hives, skin sensitivity to the sun, a high temperature, flushing, difficulty in breathing or tiredness.