Table of Contents
Executive Resume 1
Introduction 1
Drug discovery 2
Pharmaceutical Formulation 2
Dosage 4
Analytical Testing 5
Manufacturing & Production (DRAFT) 5
1.0 Manufacturing and Production Process 6
LARGE SCALE PRODUCTION 9
2.0 Manufacturing Quality Control 9
Ethics and Regulations 10
Clinical Research 11
Clinical Trials 13
Regulations 15
Conclusion 16
References 16
Introduction
Opioids are a class of medication that relieve pain by manipulating the intensity of the pain signals sent to the brain. These drugs are originally derived from the opium poppy, Papaver Somniferum. Morphine falls under this class of medication, as it is derived from the opium poppy seed and acts directly on the …show more content…
Which is the cytoplasm of specialized cells known as laticifers that are associated with the phloem (phloem is the living tissue that carries organic nutrients) throughout the plant. (Onoyovwe, et al., 2013) The traditional method for the separation of the latex starts by cutting the unripe seed capsules of the poppy plant and collecting the latex, which then oxidizes and dries as raw opium. Another method of collecting the latex involves the harvesting of the opium poppy crops after the plants have been dried in the field, which locks the alkaloid-rick latex in the biomass (Onoyovwe, et al.,