Neoplasms Of Lung Cancer
-Malignant neoplasms of the lung:
a) Primary lung tumors: Lung cancers are divided into two categories based on predominant cell type:
- Non-small cell lung carcinomas (NSCLC): There are three common types of non small cell lung cancer. These are grouped together because they behave in a similar way and respond to treatment in a different way to small cell lung cancer.(58, 59)
i) Adenocarcinoma: Now the most frequent primary lung cancer. It is usually the type of lung cancer found in non-smokers, and is the most common type seen in women. It starts in the periphery of the lungs, typically as a multilobulated mass and can be present for a long time before it is detected. May arise in scar tissue: scar carcinoma. A less common form of adenocarcinoma is bronchioloalveolar carcinoma (BAC). This …show more content…
These are usually slow growing, with late metastasis predominately to the liver, adrenal glands, kidneys and bones. Tumors usually range in size from 1 to 10 cm. They are typically found in the central bronchi, although one third occur beyond the segmental bronchi. The most characteristic radiographic appearances are a cavitating lung mass or as a peripheral nodule.(58,59) iii) Large cell carcinoma: Usually presents as large (>70% are >4cm at initial diagnosis) peripheral mass lesions and tend to grow rapidly. Overall uncommon tumor.(58,59)
- Small cell lung carcinoma (SCLC): Twenty to 25% of all lung cancers are small cell lung carcinoma. They probably arise from neuroendocrine cells and contain neurosecretory granules and may produce peptide hormones. The tumors are usually located centrally, and mediastinal extension is common and often extensive with encasement of mediastinal structures and trachea-bronchial compression. The less commonly described peripheral SCLC is often associated with hilar adenopathy and atelectasis secondary to main stem bronchus
a) Primary lung tumors: Lung cancers are divided into two categories based on predominant cell type:
- Non-small cell lung carcinomas (NSCLC): There are three common types of non small cell lung cancer. These are grouped together because they behave in a similar way and respond to treatment in a different way to small cell lung cancer.(58, 59)
i) Adenocarcinoma: Now the most frequent primary lung cancer. It is usually the type of lung cancer found in non-smokers, and is the most common type seen in women. It starts in the periphery of the lungs, typically as a multilobulated mass and can be present for a long time before it is detected. May arise in scar tissue: scar carcinoma. A less common form of adenocarcinoma is bronchioloalveolar carcinoma (BAC). This …show more content…
These are usually slow growing, with late metastasis predominately to the liver, adrenal glands, kidneys and bones. Tumors usually range in size from 1 to 10 cm. They are typically found in the central bronchi, although one third occur beyond the segmental bronchi. The most characteristic radiographic appearances are a cavitating lung mass or as a peripheral nodule.(58,59) iii) Large cell carcinoma: Usually presents as large (>70% are >4cm at initial diagnosis) peripheral mass lesions and tend to grow rapidly. Overall uncommon tumor.(58,59)
- Small cell lung carcinoma (SCLC): Twenty to 25% of all lung cancers are small cell lung carcinoma. They probably arise from neuroendocrine cells and contain neurosecretory granules and may produce peptide hormones. The tumors are usually located centrally, and mediastinal extension is common and often extensive with encasement of mediastinal structures and trachea-bronchial compression. The less commonly described peripheral SCLC is often associated with hilar adenopathy and atelectasis secondary to main stem bronchus