Intraventricular hemorrhage (IVH) is one of the most common neurological disorders in newborns. It is characterized by bleeding inside or around the ventricles. These are the spaces in the brain containing the cerebral spinal fluid. Intraventricular hemorrhage is most common in premature babies, especially very low birthweight babies weighing less than four pounds. 1 Experts are not clear as to why IVH occurs. Bleeding can occur because blood vessels in a premature baby 's brain are very fragile and immature and easily rupture. Babies with respiratory problems or other complications of prematurity are more likely to have IVH. The smaller and more premature the baby, the more likely IVH will occur. Nearly all IVH occurs within the first four days of life. Bleeding in the brain can put pressure on the nerve cells and damage them. Severe damage to cells can lead to brain injury. 2
The amount of bleeding varies, and IVH is often described in four levels. In the first level, bleeding occurs just in a small area of the ventricles. In the second level, bleeding also occurs inside the ventricles. Level three occurs when ventricles are enlarged by the blood, and level four is characterized by bleeding into the brain tissues around the ventricles. Levels one and two are most common, and often there are no further complications. Levels three and four are the most serious and may result in long-term brain injury to the baby. 3
There are many
References: Adcock, Lisa. Management and Complications of Intraventricular Hemorrhage in the Newborn, UpToDate (2012), http://www.uptodate.com/contents/management-and-complications-of-intraventricular-hemorrhage-in-the-newborn Bartoshesky, Louis Bodamer, Olaf. Maple Syrup Urine Disease Treatment and Management, Medscape (Jan. 2012), http://emedicine.medscape.com/article/946234-treatment Castek, Jaclyn Chang, Celia. Menkes Disease, Medscape (Feb. 2012), http://emedicine.medscape.com/article/1180460-overview Cloe, Adam Dean, Andrew. Periventricular Leukomalacia, Wiley Online Library (Sept. 2008), http://onlinelibrary.wiley.com/doi/10.1046/j.1440-1789.2002.00438.x/abstract Englert, Chad Haldeman, Chad. Maple Syrup Urine Disease, New York Times Health Guide (May 15, 2011), http://health.nytimes.com/health/guides/disease/maple-syrup-urine-disease/overview.html Lee, Kimberly Roberts, R. Newborn Screening Case Management Galactosemia Handbook, Texas DHS (Jan. 2011), http://www.dshs.state.tx.us/newborn/handbook.shtm Robin, Suzanne Sia, Michael. How Long Should Galactosemia Last, HealthTap (Sep. 2009), <https://www.healthtap.com/#topics/how-long-should-galactosemia-last>. Warf, Benjamin. Intraventricular Hemorrhage, Boston Children’s Hospital (2011), http://www.childrenshospital.org/az/Site1185/mainpageS1185P0.html Warf, Benjamin