New Toll to Predict Chronic Hepatitis C Treatment

Archives Des Sciences

Vol 66, No. 5;May 2013

Title: New Toll to Predict Chronic Hepatitis C Treatment
Result for Each Patient

Ieva Tolmane (Corresponding author)
Latvian University, Riga, Latvia
Riga East university hospital, Infectology Center of Latvia, Riga, Latvia
Address: Linezera Street 3, Riga, Latvia, LV 1006
Phone: [phone], Fax: [phone]
E-mail: [e-mail], [e-mail]

Baiba Rozentale
Riga Stradin’s University, Infectology and Dermatology department, Riga, Latvia
Riga East university hospital, Infectology Center of Latvia, Riga, Latvia
Address: Linezera Street 3, Riga, Latvia, LV 1006
Phone: [phone], Fax: [phone]
E-mail: [e-mail]

Jazeps Keiss
Riga East university hospital, Infectology Center of Latvia, Riga, Latvia
Address: Linezera Street 3, Riga, Latvia, LV 1006
Phone: [phone], Fax: [phone]
E-mail: [e-mail]

Andrejs Ivanovs
Riga Stradin’s University, Infectology and Dermatology department, Riga, Latvia
Phone: [phone]

498

ISSN 1661-464X

Archives Des Sciences

Vol 66, No. 5;May 2013

E-mail: [e-mail]

Raimonds Simanis
Riga Stradin’s University, Infectology and Dermatology department, Riga, Latvia
Phone: [phone]
E-mail: [e-mail]

The research is financed by European Social Found as a bursary for corresponding author.

Abstract
Background & Aims: With the standard treatment sustained virology response (SVR) can be achieved in only 54 to 63% of patients. There are many factors influencing therapy result.
The aim of this study was to develop method to prognosticate SVR in patients with chronic viral hepatitis C.
Methods: There were 264 chronic hepatitis C patients included in the study. All patients received standard treatment with interferon plus ribavirin and were divided into 2 groups – 140 (53%) responders, 124 (47%) non-responders. We analyzed 30