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Non-Alcoholic Fatty Liver Disease

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Non-Alcoholic Fatty Liver Disease
For the past few decades there has been a chronic disease plaguing society’s young children. This chronic disease has spread worldwide with the numbers of diseased children is expected to increase in the next decade. This chronic disease is obesity. Along with the rise of obesity among youth, there is a new silent killer linked to childhood obesity. This new chronic disease, typically found in alcoholics, is now becoming prevalent in obese children and is called non-alcoholic fatty liver disease (NAFLD). NAFLD is defined as a liver disease in people who have not consumed alcohol in significant amounts to cause liver damage, and in whom no other etiology for fatty liver is present (Prashant, 2007, p. 401). Ulrich, an MD at the Birmingham children’s hospital, stated, “The term NAFLD covers a spectrum of non-alcoholic fatty liver disease from benign static disease to more aggressive forms that can progress to cirrhosis within childhood” (Ulrich, 2006, p.264). The first report of NAFLD was reported in young obese children during the early 1980’s, and has been seen in children as young as nine years old. Since then, there has not been enough attention paid to NAFLD, and there is a lot to be understood about this chronic disease. To understand NAFLD, researchers and doctors need to investigate on the prevalence, pathogenesis, and detection of NAFLD in obese children. Since the first report of NAFLD came out in the 1980’s, there has been an increase in childhood obesity which has resulted in the increase of NAFLD in children. The prevalence of NAFLD in obese children has been reported to range from 20 to 77% (Prashant, 2007, p.402). NALFD has been reported in all genders, age groups and ethnicities worldwide. The ethnicities that are at higher risk for developing NAFLD are the Hispanic and Asian populations. Also, studies indicate that males are more at risk of getting NALFD then females. Findings by Sagi, an MD in children pediatrics, showed the increase in liver


References: Giorgio, R., Wolfgang, K., Joseph, S., & Klaus, P (2005). Non-alcoholic fatty liver disease in obese children evaluated by magnetic resonance imaging. Taylor & Francis group, 95, 833-837. Retrieved October 6, 2008, from the PubMed database. Kerkar, N. (2004). Non-alcoholic steatohepatits in children. Pediatic Transplantation, 8, 613- 618. Retrieved September 30, 2008, from the Academic Search Premier database. Marion, A., Baker, A J., & Dhawan, A. (2004). Fatty liver disease in children. Archives Disease Childhood, 89, 648-652. Retrieved September 30, 2008, from the Academic Premier database. Prashant, M., Monoja, D., & Narendra, A.(2007). Non-Alcoholic Fatty Liver disease and Childhood Obesity. The Indian Journal of Pediatrics, 74, 401-406. Retrieved September 30, 2008, from the Academic Search Premier data base. Roberts, E.A. (2007). Pediatric nonalcoholic fatty liver disease (NAFLD): A “growing” problem? Journal of Heptaology, 46, 1133-1142. Retrieved September 30, 2008, from the PubMed database. Sagi, R., Neuman, G., Webb, M., Philip, M., & Shalitin, S. (2007). Nonalcoholic fatty liver disease in overweight children and adolescents. Journal Compilation, 96, 1209-1213. Retrieved October 6, 2008, from the PubMed database. Ulrich, B., & Rachel, B. (2006). Non-alocholic fatty liver disease in childhood. Br J Diabetes Vasc Dis, 6, 264-268. Retrieved October 7, 2008, from the PubMed database.

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