There many forms of treatment to cure depression, many of which are biological. These target the physical and chemical side of the body.
Anti-depressants and other drugs are the most common forms of treating depression. They work by boosting levels of insufficient neurotransmitters such as serotonin and nor-adrenaline. They will either reduce the amount of re-absorption or block the enzyme that is trying to break down neurotransmitters. Allowing to increase the amount of neurotransmitter available , so that neighbouring cells become excited.
Tricyclics are used to block the transporter mechanism that re-absorbs both serotonin and nor-adrenaline into the pre-synaptic cell after it has fired. As a result to this there are more neurotransmitters left in the synapse making the transmission of the next impulse easier.
The treatment of depression has three phases which it is to go through, the first being acute in which the treatment of current symptoms takes place. Then it goes into the continuation phase in which the treatment is continued for six months where the medication is gradually withdrawn to prevent relapse. Lastly the maintenance phase which is recommended for individuals who have a reccurent depressive episode.
One of the most common anti-depressant drugs used are Selective Serotonin Re-uptake Inhibitors (SSRI's), these are associated with serotonin which have been found to be involved in depression. The SSRI's will work by stopping the nerve cells from re-absorbing serotonin that has been released into the synapse, which in turn will increase the amount of serotonin available.
However SSRI anti-depressants may not be able to treat all forms of depression. Kirsch et al (2008) found that only in the most severe cases of depression there was a significant advantage of using the SSRI. Therefore showing that anti-depressants may not be able to help those with mild or