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There is no established permanent cure for Schizophrenia, but there are a variety of therapies which help prevent schizophrenic episodes and also help sufferers deal with their mental illness. One of the main types of therapy used is drug therapy. Drug therapy involves issuing a patient psychotherapeutic drug(s) which are used to alter the chemical functioning of the brain by affecting the action of neurotransmitters. Neurotransmitters transmit signals between nerve cells called synapses. Neurotransmitters lead to changes in moods, feelings, perception and behaviour. The main category of drugs used for treating Schizophrenia is anti-psychotic drugs or neuroleptics. These lessen psychotic symptoms such as delusions and hallucinations, examples of these drugs could be chlorpromazine or clozapine.
Typical antipsychotic drugs (neuroleptics) work by reducing dopamine within schizophrenia sufferers. Common forms of neuroleptics include drugs such as Thorazine, Prolixin and Haldol. These drugs actually block the activity of the dopamine neurotransmitter, the drugs take effect within 48 hours but it can be several weeks before a noticeable difference is seen with symptom reduction. Barondes’s (1993) research looked into balancing the dosage of the drug, lowering the drug dosage reduced the side effects but also reduced the effectiveness of the drug meaning it wouldn’t necessarily be a successful or quick recovery compared to high dosages of the neuroleptics. Although this showed clear evidence for the effectiveness of neuroleptics in combating schizophrenia, emphasized when changing the dosage changes the effectiveness of the neuroleptics.
Comer’s (2001) research study looked into the effectiveness of the drugs, and found that for the majority of schizophrenia sufferers the drugs were effective and are the most successful treatment as they are more effective as a single